Yongae Baek; Myungsun Yi

doi:10.4040/jkan.2015.45.4.604

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Original Article
Factors Influencing Quality of Life during Chemotherapy for Colorectal Cancer Patients in South Korea: Yongae Baek, Myungsun Yi; Journal of Korean Academy of Nursing 2015;45(4):604-612.
DOI: https://doi.org/10.4040/jkan.2015.45.4.604
Published online: August 31, 2015

¹Asan Medical Center, Seoul, Korea.

²College of Nursing · Research Institute of Nursing Science, Seoul National University, Seoul, Korea.

Address reprint requests to: Yi, Myungsun. College of Nursing · Research Institute of Nursing Science, Seoul National University, 103 Daehag-ro, Jongon-gu, Seoul 03080, Korea. Tel: +82-2-740-8829, Fax: +82-2-765-4103, donam@snu.ac.kr

• Received: January 6, 2015 • Revised: January 31, 2015 • Accepted: June 2, 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution NoDerivs License. (http://creativecommons.org/licenses/by-nd/4.0/) If the original work is properly cited and retained without any modification or reproduction, it can be used and re-distributed in any format and medium.

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Abstract
NOTES
REFERENCES

Abstract

Purpose
The purpose of this study was to investigate the levels of physical symptoms, anxiety, depression, and quality of life (QOL) during chemotherapy for colorectal cancer patients in South Korea and to identify factors influencing their QOL.
Methods
Data were collected from 144 colorectal cancer patients receiving chemotherapy during 2012 at one general hospital located in Seoul. Physical symptoms were measured by the M. D. Anderson Symptom Inventory-Gastrointestinal Cancer Module, and anxiety and depression were measured by the Hospital Anxiety Depression Scale. QOL was measured by the Functional Assessment of Cancer Therapy-Colorectal. Data were analyzed using descriptive statistics, t-test, one-way ANOVA, Scheffé post hoc test, Pearson correlation and stepwise multiple regression.
Results
Mean age of the participants was 56.6 and most of them were not employed. In terms of cancer stage, 38.2% were in stage 3, followed by stage 4 (34.7%). The most frequent symptom was lack of appetite, followed by sleep disturbance and fatigue. The mean score for anxiety was 5.40 with a prevalence of 23% and that of depression 8.85 with a prevalence of 64.6%. The mean score for quality of life was 81.93 out of 136 and 75.3% of the variance in QOL was explained by depression, symptoms, anxiety, treatment place, and occupational status. Depression was the strongest predictive factor.
Conclusion
Oncology professionals need to pay special attention to relieving depression as well as physical symptoms to improve QOL during chemotherapy for colorectal cancer patients.
Keywords: Colorectal cancer; Quality of life; Symptom; Anxiety; Depression

This manuscript is based on the part of the first author's master's thesis from Seoul National University.

REFERENCES

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Table 1

Sociodemographic Characteristics of the Participants (N=144)

Table 2

Disease-related Characteristics of the Participants (N=144)

Op=Operation; RT=Radiation therapy.

Table 3

Scores of Symptoms and Disturbance (N=144)

^*Between 5 and 6 on a 0~10 scale; ^†7 or greater on a 0~10 scale.

Table 4

Scores of Anxiety, Depression and Quality of Life (N=144)

Table 5

Factors Influencing Quality of Life (N=144)

Figure & Data

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Factors Influencing Quality of Life during Chemotherapy for Colorectal Cancer Patients in South Korea

J Korean Acad Nurs. 2015;45(4):604-612. Published online August 31, 2015

DOI: https://doi.org/10.4040/jkan.2015.45.4.604

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Factors Influencing Quality of Life during Chemotherapy for Colorectal Cancer Patients in South Korea

Table 1

Sociodemographic Characteristics of the Participants (N=144)

Table 2

Disease-related Characteristics of the Participants (N=144)

Op=Operation; RT=Radiation therapy.

Table 3

Scores of Symptoms and Disturbance (N=144)

^*Between 5 and 6 on a 0~10 scale; ^†7 or greater on a 0~10 scale.

Table 4

Scores of Anxiety, Depression and Quality of Life (N=144)

Table 5

Factors Influencing Quality of Life (N=144)

Table 1 Sociodemographic Characteristics of the Participants (N=144)

Table 2 Disease-related Characteristics of the Participants (N=144)

Op=Operation; RT=Radiation therapy.

Table 3 Scores of Symptoms and Disturbance (N=144)

^*Between 5 and 6 on a 0~10 scale; ^†7 or greater on a 0~10 scale.

Table 4 Scores of Anxiety, Depression and Quality of Life (N=144)

Table 5 Factors Influencing Quality of Life (N=144)