Seong Min Kim; Hyun-Ju Seo; Mi Ra Sung

doi:10.4040/jkan.2014.44.4.391

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Original Article
Factors Affecting Dementia Prevalence in People Aged 60 or Over: A Community based Cross-sectional Study: Seong Min Kim, Hyun-Ju Seo, Mi Ra Sung; Journal of Korean Academy of Nursing 2014;44(4):391-397.
DOI: https://doi.org/10.4040/jkan.2014.44.4.391
Published online: August 29, 2014

¹Department of Nursing, Seonam University, Namwon·Graduate school, Chosun University, Gwangju, Korea.

²Department of Nursing, College of Medicine, Chosun University, Gwangju, Korea.

³Department of Nursing, Yongin Songdam College, Yongin·Seoul Metropolitan Center for Dementia, Seoul, Korea.

Address reprint requests to: Seo, Hyun-Ju. Department of Nursing, College of Medicine, Chosun University, 309 Pilmum-daero, Dong-gu, Gwangju 501-759, Korea. Tel: +82-62-230-6320, Fax: +82-62-230-6329, hjseo10@chosun.ac.kr

• Received: April 8, 2014 • Revised: May 2, 2014 • Accepted: June 28, 2014

This is an Open Access article distributed under the terms of the Creative Commons Attribution NoDerivs License. (http://creativecommons.org/licenses/by-nd/4.0/) If the original work is properly cited and retained without any modification or reproduction, it can be used and re-distributed in any format and medium.

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Abstract
NOTES
REFERENCES

Abstract

Purpose
This study was done to examine the association between body mass index (BMI) and any type of clinical dementia.
Methods
Participants were 60,321 people over 60 years of age enrolled in the Seoul Dementia Management Project in 2011. K-MMSE was used to classify participants as having a cognitive impairment and the Clinical Dementia Rating or DSM-IV by psychiatrists or neurologists to determine whether participants were in the dementia group or the non-dementia group. Descriptive statistics, chi-square test, and binary logistic regression analysis were performed.
Results
In the univariate analysis, age, education level, living with spouse, BMI, alcohol consumption, and exercise were significantly associated with dementia. In multivariable analysis, increasing age was positively associated with dementia, and educational level was negatively associated with dementia. The exercise group had a lower prevalence of dementia than the non-exercise group. The odds ratio of dementia in the over-weight and obese groups compared to the normal group was 0.85 (95% CI 0.60, 0.98) and 0.64 (95%CI 0.46, 0.75), respectively.
Conclusion
Results indicate that dementia is negatively associated with increasing BMI in people aged 60 years or older, but a prospective cohort study is needed to elucidate the causal effect relationship between BMI and dementia.
Keywords: Body mass index; Dementia; Association

This study was supported by a grant from the Chosun University, Gwangju, Republic of Korea (K206125001).

REFERENCES

1. Statistics Korea. Elderly statistics 2010. Daejeon: Author; 2010.
2. Cho MJ. The prevalence and risk factors of dementia in the Korean elderly. Health Welf Policy Forum. 2009;156:43–48.
3. Prince M, Bryce R, Albanese E, Wimo A, Ribeiro W, Ferri CP. The global prevalence of dementia: A systematic review and metaanalysis. Alzheimers Dement. 2013;9(1):63–75.e2. http://dx.doi.org/10.1016/j.jalz.2012.11.007Article PubMed PDF
4. Ministry of Health and Welfare. 2012 survey of dementia prevalence [Internet]. Seoul, Author. 2013;cited 2013 August 16. Available from: http://www.mw.go.kr/front_new/al/sal0301vw.jsp?PAR_MENU_ID=04&MENU_ID=0403&page=1&CONT_SEQ=286138&SEARCHKEY=TITLE&SEARCHVALUE=dementia
5. Lee CN, Park KW. Risk factors of dementia. J Korean Diabetes. 2012;13(3):129–132. http://dx.doi.org/10.4093/jkd.2012.13.3.129Article
6. Johnson DK, Wilkins CH, Morris JC. Accelerated weight loss may precede diagnosis in Alzheimer disease. Arch Neurol. 2006;63(9):1312–1317. http://dx.doi.org/10.1001/archneur.63.9.1312Article PubMed
7. Albanese E, Taylor C, Siervo M, Stewart R, Prince MJ, Acosta D. Dementia severity and weight loss: A comparison across eight cohorts. The 10/66 study. Alzheimers Dement. 2013;9(6):649–656. http://dx.doi.org/10.1016/j.jalz.2012.11.014Article PubMed PDF
8. Gao S, Nguyen JT, Hendrie HC, Unverzagt FW, Hake A, Smith-Gamble V, et al. Accelerated weight loss and incident dementia in an elderly African-American cohort. J Am Geriatr Soc. 2011;59(1):18–25. http://dx.doi.org/10.1111/j.1532-5415.2010.03169.xArticle PubMed
9. Xu WL, Atti AR, Gatz M, Pedersen NL, Johansson B, Fratiglioni L. Midlife overweight and obesity increase late-life dementia risk: A population-based twin study. Neurology. 2011;76(18):1568–1574. http://dx.doi.org/10.1212/WNL.0b013e3182190d09Article PMC
10. Ghaderpanahi M, Fakhrzadeh H, Sharifi F, Mirarefin M, Badamchizade Z, Larijani B, et al. Association between late-life body mass index, waist circumference, and dementia: Kahrizak elderly study. J Am Geriatr Soc. 2012;60(1):173–174. http://dx.doi.org/10.1111/j.1532-5415.2011.03751.xArticle PubMed
11. Benito-León J, Mitchell AJ, Hernández-Gallego J, Bermejo-Pareja F. Obesity and impaired cognitive functioning in the elderly: A population-based cross-sectional study (NEDICES). Eur J Neurol. 2013;20(6):899–906. http://dx.doi.org/10.1111/ene.12083
12. Anstey KJ, Cherbuin N, Budge M, Young J. Body mass index in midlife and late-life as a risk factor for dementia: A meta-analysis of prospective studies. Obes Rev. 2011;12(5):e426–e437. http://dx.doi.org/10.1111/j.1467-789X.2010.00825.xArticle PubMed
13. Kang Y, Na DL, Hahn S. A validity study on the Korean mini-mental state examination (K-MMSE) in dementia patients. J Korean Neurol Assoc. 1997;15(2):300–308.
14. Lee YK, Sung MR, Lee DY. Comorbidity and health habits of Seoul city elders with dementia. J Korean Acad Nurs. 2011;41(3):411–422. http://dx.doi.org/10.4040/jkan.2011.41.3.411Article PubMed
15. Lee JH, Lee KU, Lee DY, Kim KW, Jhoo JH, Kim JH, et al. Development of the Korean version of the consortium to establish a registry for Alzheimer's disease assessment packet (CERAD-K): Clinical and neuropsychological assessment batteries. J Gerontol B Psychol Sci Soc Sci. 2002;57(1):P47–P53.Article PubMed
16. Kang Y, Na DL. Seoul neuropsychological screening battery (SNSB) manual. Seoul: Human Brain Research & Consulting Co; 2003.
17. Choi SH, Na DL, Lee BH, Hahm DS, Jeong JH, Yoon SJ, et al. Estimating the validity of the Korean version of expanded clinical dementia rating (CDR) scale. J Korean Neurol Assoc. 2001;19(6):585–591.
18. Chang WS, Won KH, Lee JY, Kim ET, Kweon HJ. The relationship between obesity and the high probability of dementia based on the body mass index and waist circumference. Korean J Fam Med. 2012;33(1):17–24. http://dx.doi.org/10.4082/kjfm.2012.33.1.17Article PubMed PMC
19. McDowell I, Xi G, Lindsay J, Tierney M. Mapping the connections between education and dementia. J Clin Exp Neuropsychol. 2007;29(2):127–141. http://dx.doi.10.1080/13803390600582420Article PubMed
20. Sharp ES, Gatz M. Relationship between education and dementia: An updated systematic review. Alzheimer Dis Assoc Disord. 2011;25(4):289–304. http://dx.doi.org/10.1097/WAD.0b013e318211c83cPubMed PMC
21. Lautenschlager NT, Cox KL, Flicker L, Foster JK, van Bockxmeer FM, Xiao J, et al. Effect of physical activity on cognitive function in older adults at risk for Alzheimer disease: A randomized trial. JAMA. 2008;300(9):1027–1037. http://dx.doi.org/10.1001/jama.300.9.1027Article PubMed
22. Forbes D, Thiessen EJ, Blake CM, Forbes SC, Forbes S. Exercise programs for people with dementia. Cochrane Database Syst Rev. 2013;12:CD006489. http://dx.doi.org/10.1002/14651858.CD006489.pub3Article
23. Gillette Guyonnet S, Abellan Van Kan G, Alix E, Andrieu S, Belmin J, Berrut G, et al. IANA (International Academy on Nutrition and Aging) expert group: Weight loss and Alzheimer's disease. J Nutr Health Aging. 2007;11(1):38–48.PubMed
24. Besser LM, Gill DP, Monsell SE, Brenowitz W, Meranus DH, Kukull W, et al. Body mass index, weight change, and clinical progression in mild cognitive impairment and Alzheimer disease. Alzheimer Dis Assoc Disord. 2014;28(1):36–43. http://dx.doi.org/10.1097/wad.0000000000000005Article PubMed PMC

Table 1

Participant Characteristics (N=60,321)

Table 2

Univariate Analysis of Categorical Variables related to Dementia (N=60,321)

Table 3

Factors Affecting Dementia Prevalence in Elders Aged 60 Years or Older (N=60,321)

^*p<.05 by binary logistic regression analysis.

Figure & Data

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Factors Affecting Dementia Prevalence in People Aged 60 or Over: A Community based Cross-sectional Study

J Korean Acad Nurs. 2014;44(4):391-397. Published online August 29, 2014

DOI: https://doi.org/10.4040/jkan.2014.44.4.391

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Factors Affecting Dementia Prevalence in People Aged 60 or Over: A Community based Cross-sectional Study

Table 1

Participant Characteristics (N=60,321)

Table 2

Univariate Analysis of Categorical Variables related to Dementia (N=60,321)

Table 3

Factors Affecting Dementia Prevalence in Elders Aged 60 Years or Older (N=60,321)

^*p<.05 by binary logistic regression analysis.

Table 1 Participant Characteristics (N=60,321)

Table 2 Univariate Analysis of Categorical Variables related to Dementia (N=60,321)

Table 3 Factors Affecting Dementia Prevalence in Elders Aged 60 Years or Older (N=60,321)

^*p<.05 by binary logistic regression analysis.