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Depression and Risk Factors in Patients with Crohn's Disease
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Ok-Hee Cho, Yang-Sook Yoo, Suk-Kyun Yang
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J Korean Acad Nurs 2012;42(2):207-216. Published online April 30, 2012
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DOI: https://doi.org/10.4040/jkan.2012.42.2.207
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 Abstract
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Purpose
This study was conducted to determine the risk factors among patients with depression with Crohn's disease.
Methods
Data were collected by questionnaire from 276 patients who were diagnosed with Crohn's disease at a tertiary hospital located in Seoul. Measurements included patients' demographic characteristics, clinical characteristics, depression level, and health-related quality of life. Data were analyzed using t-test, χ2-test, Wilcoxon rank sum test, and logistic regression analyses.
Results
The incidence rate of depression (BDI-II≥14scores) was 31.9% (n=88). Univariate analysis revealed that being a woman, school graduation status, economic status (low), BMI(<18.5Kg/m2), disease duration (≥3 years), CDAI (≥150 scores), frequency of hospital admission (≥2), extra-intestinal manifestation (arthralgia, stomatitis), administration of 5-aminosalicylic acid, and disease related quality of life (SIBDQ<50 scores) were associated with depression. Multivariate analysis revealed that economic status (low), school graduation status, and quality of life (SIBDQ<50 scores) were more likely to report high level of depression.
Conclusion
Future research should consider managing depression as an essential component of comprehensive care for patients with Crohn's disease. In addition, further research is needed to develop strategies to better improve quality of life among patients with Crohn's disease who are depressed.
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Citations
Citations to this article as recorded by  - Are Depression and Anxiety Underdiagnosed in Socially Vulnerable Patients With Inflammatory Bowel Disease?
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Revista da Associação Médica Brasileira (English Edition).2013; 59(2): 100. CrossRef
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