Journal of Korean Academy of Nursing

Pok-Ja Oh

3 Articles

Effectiveness of Non-Pharmacologic Interventions in Chemotherapy Induced Peripheral Neuropathy: A Systematic Review and Meta-Analysis: Pok-Ja Oh, You Lim Kim; J Korean Acad Nurs 2018;48(2):123-142. Published online January 15, 2018; DOI: https://doi.org/10.4040/jkan.2018.48.2.123

Abstract Purpose

This study was conducted to evaluate the effectiveness of non-pharmacologic interventions in chemotherapy-induced peripheral neuropathy (CIPN).

Methods

PubMed, Cochrane Library CENTRAL, EMBASE, CINAHL, and several Korean databases (Until August 2017) were searched. The main search strategy combined terms for peripheral neuropathy and presence of neoplasms. The risk of bias was assessed using the Cochrane's Risk of Bias tool for randomized studies and the Risk of Bias Assessment tool for non-randomized studies. To estimate the effect size, a meta-analysis of the studies was performed using the Rev Man 5.3 program of the Cochrane Library random-effects models were used in the analyses.

Results

Twenty-two studies with a total of 954 participants met the inclusion criteria. Of the 22 studies, 12 were used to estimate the effect size of the non-pharmacologic interventions. The non-pharmacologic interventions used in patients with CIPN were exercise, acupuncture, massage, and foot bath. The acupuncture significantly reduced CIPN symptoms and signs (d=-0.71) and CIPN pain (d=-0.73) (p<.001). Massage and foot bath were also effective in reducing CIPN symptoms (d=-0.68; 95% CI=-1.05, -0.30; p<.001; I²=19%).Exercis-es were effective in improving muscle strength and endurance(d=-0.55) and quality of life (d=-2.96), but they were not significantly effective in improving CIPN.

Conclusion

Although these results provide little evidence of the effectiveness of acupuncture, massage, and foot bath in the treatment of CIPN, they suggest that these interventions can reduce CIPN symptoms in patients with cancer. However, the findings of this study should be interpreted with caution as there is a relative lack of data in this field, and additional well-designed studies are needed. PROSPERO registration: CRD42017076278.

Citations

Citations to this article as recorded by

The Effectiveness and Safety of Nurse-Led Auricular Acupressure on Chemotherapy-Induced Peripheral Neuropathy Among Patients With Breast Cancer
Mi Sook Jung, Mijung Kim, Eun Hee Sohn, Jin Sun Lee
Cancer Nursing.2025; 48(2): E64. CrossRef
Effects of acupuncture-related intervention on chemotherapy-induced peripheral neuropathy and quality of life: An umbrella review
Mei-Ling Yeh, Chin-Che Hsu, Matthew Lin, Chuan-Ju Lin, Jaung-Geng Lin
Complementary Therapies in Medicine.2025; 89: 103131. CrossRef
Acupuncture-related interventions improve chemotherapy-induced peripheral neuropathy: A systematic review and network meta-analysis
Mei-Ling Yeh, Ru-Wen Liao, Pin-Hsuan Yeh, Chuan-Ju Lin, Yu-Jen Wang
BMC Complementary Medicine and Therapies.2024;[Epub] CrossRef
Effect of Exercise Intervention on Chemotherapy-Induced Peripheral Neuropathy Symptoms in Cancer Patients: A Meta-analysis
Nan Wu, Hongshi Cao, Shiyuan Du, Yulu Chen, Xinxin Wang, Jiong Li, Xin Peng
Cancer Nursing.2024;[Epub] CrossRef
The effectiveness and safety of acupuncture/electroacupuncture for chemotherapy-induced peripheral neuropathy: a systematic review and meta-analysis
Li-Xia Pei, Yue Yi, Jing Guo, Lu Chen, Jin-Yong Zhou, Xiao-Liang Wu, Jian-Hua Sun, Hao Chen
Acupuncture in Medicine.2023; 41(2): 73. CrossRef
Effects of Footbath on Postoperative Pain and Sleep Quality in Patients With Lumbar Degenerative Disc Disease: A Randomized Controlled Study
Seher Ünver, Ülkü Çolakoğlu, Ahmet Tolgay Akıncı
Journal of Neuroscience Nursing.2023; 55(4): 125. CrossRef
Non-pharmacological therapy for chemotherapy-induced peripheral neurotoxicity: a network meta-analysis of randomized controlled trials
Xia Zhang, Ao Wang, Miaowei Wang, Guo Li, Quan Wei
BMC Neurology.2023;[Epub] CrossRef
Effects of Manual Therapy on Chemotherapy-Induced Peripheral Neuropathy: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Eunsang Lee, Hyunjoong Kim
Physical Therapy Rehabilitation Science.2023; 12(1): 12. CrossRef
The impact of peripheral neuropathy symptoms, self-care ability, and disturbances to daily life on quality of life among gynecological cancer patients undergoing chemotherapy: a cross-sectional survey
Sohee Mun, Hyojung Park
Korean Journal of Women Health Nursing.2022; 28(4): 296. CrossRef
Development and Effects of a Mobile Application-based Self-Management Program for Chemotherapy-induced Peripheral Neuropathy in Colorectal Cancer Patients
Pok-Ja Oh, Jung Ran Lee
Korean Journal of Adult Nursing.2022; 34(3): 258. CrossRef
Treatment and diagnosis of chemotherapy-induced peripheral neuropathy: An update
Allison D. Desforges, Chance M. Hebert, Allyson L. Spence, Bailey Reid, Hemangini A. Dhaibar, Diana Cruz-Topete, Elyse M. Cornett, Alan David Kaye, Ivan Urits, Omar Viswanath
Biomedicine & Pharmacotherapy.2022; 147: 112671. CrossRef
Chemotherapy-induced peripheral neuropathy in children and adolescent cancer patients
Nicolette Tay, E-Liisa Laakso, Daniel Schweitzer, Raelene Endersby, Irina Vetter, Hana Starobova
Frontiers in Molecular Biosciences.2022;[Epub] CrossRef
A Case Report of Chemotherapy-Induced Peripheral Neuropathy Treated with Modified Guibi-tang
Su Bin Park, Jee-Hyun Yoon, Eun Hye Kim, Seong Woo Yoon
The Journal of Internal Korean Medicine.2022; 43(3): 451. CrossRef
Kanser Tedavisi Alan Çocuklarda Kemoterapiyle İlişkili Periferik Nöropatinin Değerlendirilmesinde Hemşirenin Rolü
Bilge ÖZDEMİR, Gülçin ÖZALP GERÇEKER
Dokuz Eylül Üniversitesi Hemşirelik Fakültesi Elektronik Dergisi.2022; 15(3): 369. CrossRef
Non-Pharmacological Self-Management Strategies for Chemotherapy-Induced Peripheral Neuropathy in People with Advanced Cancer: A Systematic Review and Meta-Analysis
Megan Crichton, Patsy M. Yates, Oluwaseyifunmi Andi Agbejule, Amy Spooner, Raymond J. Chan, Nicolas H. Hart
Nutrients.2022; 14(12): 2403. CrossRef
The Effects of Foot Reflexology on the Physical Symptoms of Cancer Patients
Young-Ran Yeun, Yi-Sub Kwak, Hye-Young Kim
Exercise Science.2021; 30(1): 8. CrossRef
A Case Report of Chemotherapy-Induced Peripheral Neuropathy Treated with Warm Needling
Jee-Hyun Yoon, Su Bin Park, Jee Young Lee, Eun Hye Kim, Seong Woo Yoon
The Journal of Internal Korean Medicine.2021; 42(2): 114. CrossRef
The Effect of Self-Acupressure on Peripheral Neuropathy, Disturbance in Daily Activity, and Quality of Life in Breast Cancer Patients undergoing Chemotherapy
Su Young Kim, Jeong Sook Park
Asian Oncology Nursing.2021; 21(3): 129. CrossRef
Effects of Exercise on Chemotherapy-induced Peripheral Neuropathy: A Systematic Review and Meta-Analysis
Yu Hyeon Choe, Da Hye Kim
Korean Journal of Adult Nursing.2021; 33(5): 458. CrossRef
Effects of pain neuroscience education on kinesiophobia in patients with chronic pain: a systematic review and meta-analysis
Hyunjoong Kim, Seungwon Lee
Physical Therapy Rehabilitation Science.2020; 9(4): 309. CrossRef
Prescribing for persistent cancer pain: focus on chemotherapy-induced peripheral neuropathy
Martin Galligan
Journal of Prescribing Practice.2020; 2(4): 176. CrossRef
Effects of Nonpharmacological Interventions in Chemotherapy-Induced Peripheral Neuropathy: An Overview of Systematic Reviews and Meta-Analyses
Jie Hao, Xiaoshu Zhu, Alan Bensoussan
Integrative Cancer Therapies.2020;[Epub] CrossRef
Clinical study on concurrent use of electro-acupuncture or Chuna manual therapy with pregabalin for chemotherapy-induced peripheral neuropathy: safety and effectiveness (open-labeled, parallel, randomized controlled trial, assessor-blinded)
Jin-Hyun Lee, Tae jin Cho, Min Geun Park, Ji-Hoon Kim, Sung Kyu Song, Shin-Young Park, Yun-Young Sunwoo, Ilkyun Lee, Tae-Yong Park
Medicine.2020; 99(3): e18830. CrossRef
The Experience of Chemotherapy-induced Peripheral Neuropathy in People with Cancer
Pok Ja Oh, Eun Sook Choi, Jin Lee
Asian Oncology Nursing.2019; 19(2): 81. CrossRef
Acupuncture therapy improves health-related quality of life in patients with chronic obstructive pulmonary disease: A systematic review and meta-analysis
Po-Chun Hsieh, Mei-Chen Yang, Yao-Kuang Wu, Hsin-Yi Chen, I-Shiang Tzeng, Pei-Shan Hsu, Chang-Ti Lee, Chien-Lin Chen, Chou-Chin Lan
Complementary Therapies in Clinical Practice.2019; 35: 208. CrossRef
Acupuncture for the Relief of Chronic Pain: A Synthesis of Systematic Reviews
Carole A. Paley, Mark I. Johnson
Medicina.2019; 56(1): 6. CrossRef
Evidence, safety and recommendations for when to use acupuncture for treating cancer related symptoms: a narrative review
Stephen Birch, Myeong Soo Lee, Terje Alraek, Tae-Hun Kim
Integrative Medicine Research.2019; 8(3): 160. CrossRef
Physiotherapy management of chemotherapy induced peripheral neuropathy in a gynecological condition through clinical reasoning process: A case study
K. M. Amran Hossain, Mohammad Anwar Hossain, Feroz Ahmed Mamin, Ehsanur Rahman, Nasrin Afroz, Nusrat Jahan Sonia, Shati Aziz Khan
Edorium Journal of Disability and Rehabilitation.2018; 4(2): 1. CrossRef
Research Trend about Complementary and Alternative Therapy in Korea using Text Network Analysis
Hae Ree Sung, Jung Lim Lee, Youngji Kim, Jeong Sig Kim
The Korean Journal of Rehabilitation Nursing.2018; 21(2): 61. CrossRef
Síntesis de la evidencia científica en acupuntura
Juan Muñoz-Ortego, Jorge Vas, Betina Nishishinya Aquino, Beltrán Carrillo, Alberto Pérez Samartín, Cristina Verástegui, Rafael Cobos
Revista Internacional de Acupuntura.2018; 12(4): 97. CrossRef

640 View
22 Download
30 Crossref

Meta-Analysis of Spiritual Intervention Studies on Biological, Psychological, and Spiritual Outcomes: Pok-Ja Oh, Young-Hyun Kim; J Korean Acad Nurs 2012;42(6):833-842. Published online December 31, 2012; DOI: https://doi.org/10.4040/jkan.2012.42.6.833

Abstract PDF

Purpose

The purpose of this study was to evaluate the effectiveness of spiritual intervention studies by examining biological, psychological, and spiritual outcomes.

Methods

From electronic databases 2522 studies were retrieved, of which 21 studies met the inclusion criteria. These studies had 1411 participants. Two authors independently extracted data from the selected studies and assessed the methodological quality. The data were analyzed using the RevMan 5.1 program of the Cochrane library.

Results

Overall effect size of spiritual intervention on spiritual and psychological (depression and anxiety) outcomes were moderate (d=-0.65 to d=-0.76, p<.001). The effects on biological outcomes (pain and functional status) ranged from -0.51 to -0.39, respectively. No publication bias was detected as evaluated by a funnel plot. Spiritual intervention had a moderate effect on psychological and spiritual outcomes and a smaller effect on biological outcomes.

Conclusion

The results of this study suggest that spiritual intervention can relieve depression and anxiety. Further randomized controlled trials studies are needed to evaluate the effects of spiritual intervention on biological outcomes.

Citations

Citations to this article as recorded by

Effectiveness of Interventions on Death Anxiety and Fear in Adults with Chronic Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Merve Gulbahar Eren, Kübra Üçgül, Havva Sert
OMEGA - Journal of Death and Dying.2023;[Epub] CrossRef
Effects of counselling and spiritual care program on anxiety in patients with chronic diseases: A systematic review and meta-analysis
Nader Salari, Mohsen Kazeminia, Alireza Abdi, Amir Abdolmaleki, Nasrin Abdoli, Masoud Mohammadi, Shamarina Shohaimi
Current Psychology.2023; 42(12): 9943. CrossRef
The development of a Cancer Pain Belief Modification Program for patients with oral cancer in China: a feasibility study
Rongna Wang, Xiaoyan Zheng, Xixi Su, Xiuyu Huang, Huangju Liu, Yulai Guo, Ji Gao
BMC Nursing.2023;[Epub] CrossRef
The Effects of Spiritual Well-being on Self-care Practices in People Undergoing Hemodialysis: The Mediating Effect of Hope
Bu Kyung Kim, Pok-Ja Oh
Korean Journal of Adult Nursing.2022; 34(6): 592. CrossRef
Abriendo nuevas puertas: Relevancia clínica de integrar la religión y la espiritualidad en la disciplina de la psicología
Orlando M. Pagan-Torres Ponce
Revista Puertorriqueña de Psicologia.2022; 33(2): 258. CrossRef
The Mediating Effect of Depression on the Relationship between Social Support, Spirituality and Burnout in Family Members of Patients with Cancer
Won-Hee Jun, Kyung-Sook Cha, Kee-Lyong Lee
International Journal of Environmental Research and Public Health.2021; 18(4): 1727. CrossRef
Spirituality, religiousness, and mental health: A review of the current scientific evidence
Giancarlo Lucchetti, Harold G Koenig, Alessandra Lamas Granero Lucchetti
World Journal of Clinical Cases.2021; 9(26): 7620. CrossRef
Analysis of Spiritual Care Experiences of Acute-Care Hospital Nurses
Ga Eon Lee, KyoungMi Kim
The Korean Journal of Hospice and Palliative Care.2020; 23(2): 44. CrossRef
The Effect of Religion Intervention on Life Satisfaction and Depression in Elderly with Heart Failure
Alireza Abdi, Askar Soufinia, Milad Borji, Asma Tarjoman
Journal of Religion and Health.2019; 58(3): 823. CrossRef
Initial Assessment and Care Planning in Palliative Hospice Care: Focus on Assessment Tools
Eun Ju Park, Su Jin Koh, Jae Kyung Cheon
The Korean Journal of Hospice and Palliative Care.2019; 22(2): 67. CrossRef
Experience of Cancer Patients Receiving Spiritual Nursing Care in one Christian General Hospital
Eun Youngi Seo, Suhye Kwon, Youngkyoung Kim, ALeum Han
Asian Oncology Nursing.2019; 19(3): 179. CrossRef
Complementary religious and spiritual interventions in physical health and quality of life: A systematic review of randomized controlled clinical trials
Juliane Piasseschi de Bernardin Gonçalves, Giancarlo Lucchetti, Paulo Rossi Menezes, Homero Vallada, Gianni Virgili
PLOS ONE.2017; 12(10): e0186539. CrossRef
Panorama das pesquisas em ciência, saúde e espiritualidade
Alexander Moreira-Almeida, Giancarlo Lucchetti
Ciência e Cultura.2016; 68(1): 54. CrossRef
Spirituality is associated with better prostate cancer treatment decision making experiences
Michelle A. Mollica, Willie Underwood, Gregory G. Homish, D. Lynn Homish, Heather Orom
Journal of Behavioral Medicine.2016; 39(1): 161. CrossRef
Validity and Reliability of Korean Version of the Spiritual Care Competence Scale
Mi Ja Chung, Youngrye Park, Young Eun
Journal of Korean Academy of Nursing.2016; 46(6): 871. CrossRef
Influence of Self-esteem, Empathy and Existential Well-being on Spiritual Care Competence in Nursing Students
Jin Kim, Sookyung Choi
Journal of Korean Academy of Fundamentals of Nursing.2015; 22(3): 328. CrossRef
Religious and spiritual interventions in mental health care: a systematic review and meta-analysis of randomized controlled clinical trials
J. P. B. Gonçalves, G. Lucchetti, P. R. Menezes, H. Vallada
Psychological Medicine.2015; 45(14): 2937. CrossRef
The Effects of Spiritual Interventions in Patients With Cancer: A Meta-Analysis
Pok-Ja Oh, Soo Hyun Kim
Oncology Nursing Forum.2014; 41(5): E290. CrossRef
Association between Spiritual Well-Being and Pain, Anxiety and Depression in Terminal Cancer Patients: A Pilot Study
Yong Joo Lee, Chul-Min Kim, John A. Linton, Duk Chul Lee, Sang-Yeon Suh, Ah-Ram Seo, Hong-Yup Ahn
The Korean Journal of Hospice and Palliative Care.2013; 16(3): 175. CrossRef
Meta-analysis of Psychosocial Interventions to Reduce Pain in Patients with Cancer
Pok Ja Oh, Suk Jung Han
Journal of Korean Academy of Nursing.2013; 43(5): 658. CrossRef
Effect of Intervention Programs for Improving Maternal Adaptation in Korea: Systematic Review
Hee Sun Kang, Soo Young Yeom, Eun-Young Jun
Korean Journal of Women Health Nursing.2013; 19(3): 153. CrossRef

213 View
1 Download
21 Crossref

Predictors of Fighting Spirit or Helplessness/Hopelessness in People with Cancer: Pok-Ja Oh, Yeon-Joo Lee; Journal of Korean Academy of Nursing 2008;38(2):270-277. Published online April 30, 2008; DOI: https://doi.org/10.4040/jkan.2008.38.2.270

Abstract PDF

Purpose

This study was done to identify predictors of the fighting spirit or helplessness/hopelessness in the patients' mental adjustment to cancer. Cancer patients' characteristics like performance status, metastasis and duration of diagnosis with demographic factors, spiritual support and social support were used as predictors of a fighting spirit or helplessness/hopelessness.

Methods

total of 124 ambulatory cancer patients completed the Mental Adjustment to Cancer (MAC) scale and responded in a structured instrument about their characteristics, spiritual and social support.

Results

The results of multiple regression analysis revealed that confidence in the supporter (R²=.114, p=.000), duration of cancer diagnosis (R²=.041, p=.000) and faith (R²=.030, p=.000) were predictive of a fighting spirit (R²=.185, p=.000); whereas, education (R²= .074, p=.001), performance status (R²=.055, p=.000), satisfaction with social support (R²=.046, p=.000), and metastasis (R²=.037, p=.000) were predictive of helplessness/hopelessness (R²=.202, p=.000).

Conclusion

Social support, spiritual support and disease related factors like metastasis, performance status, and duration of cancer diagnosis need to be considered in a psychosocial nursing intervention for a fighting spirit or helplessness/hopelessness.

Citations

Citations to this article as recorded by

What is the direction of the association between social support and coping in cancer patients? A systematic review
Rossella Bottaro, Giuseppe Craparo, Palmira Faraci
Journal of Health Psychology.2023; 28(6): 524. CrossRef
Concept Analysis of Fighting Spirit in Korean Patients with Cancer
Kyung Ok Kim, Jung A Kim
Korean Journal of Adult Nursing.2019; 31(1): 50. CrossRef
Disturbance in ADL from Chemotherapy-induced Peripheral Neuropathy and Quality of Life in Cancer Patients: The Mediating Effect of Psychological Distress
Kyung Yeon Kim, Seung Hee Lee, Jeong Hye Kim, Pok Ja Oh
Journal of Korean Academy of Nursing.2015; 45(5): 661. CrossRef

162 View
2 Download
3 Crossref

Author index