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Original Article
- Transition of Symptoms and Quality of Life in Cancer Patients on Chemotherapy
- Min Young Kim
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Journal of Korean Academy of Nursing 2009;39(3):433-445.
DOI: https://doi.org/10.4040/jkan.2009.39.3.433
Published online: June 29, 2009
Researcher, Jeju Regional Cancer Center, Jeju National University Hospital, Jeju, Korea.
- Address reprint requests to: Kim, Min Young. 107-204 Daelin APT, 800 Donam-dong, Jeju 690-806, Korea. Tel: 82-64-717-1508, Fax: 82-64-717-1487, musemy2@hanmail.net
• Received: August 27, 2008 • Accepted: June 2, 2009
Copyright © 2009 Korean Society of Nursing Science
Abstract
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Purpose
- The purpose of this study was to assess changes in pain, fatigue, anorexia, anxiety and quality of life (QOL) in patients with cancer who were on chemotherapy.
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Methods
- Symptoms and QOL were examined both before chemotherapy and after 2 cycles of chemotherapy. The participants were 76 cancer patients receiving chemotherapy in one of 7 hospitals.
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Results
- The patients experienced a mean of 2.22-2.23 symptoms out of 4 symptoms. Patients who were female, or suffered from breast or colorectal cancer experienced more symptoms. Fatigue at present, and most severe fatigue and anorexia in the previous 3 weeks increased significantly. Anxiety and QOL decreased significantly after 2 cycles of chemotherapy. Number of symptoms, anorexia at present, most severe anorexia in past 3 weeks, and anxiety had negative correlations. QOL before chemotherapy showed a positive correlation with QOL after 2 cycles of chemotherapy. In a regression analysis, anxiety, QOL at baseline, income, and the most severe pain in the past 3 weeks were significant predictors of QOL.
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Conclusion
- Physical and psychological factors were significant predictors of both QOL and each subscale, and these factors correlated with each other. These results demonstrate the needs for early assessment and intervention from the start of chemotherapy to decrease symptoms and improve QOL.
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REFERENCES
Table 5Correlation between Number of Symptom, Each symptom and QOL
*Before chemotherapy; †After 2 cycles chemotherapy.
Sx.=Number of symptoms; Pa1=pain at present; Pa2=most severe pain in past 3 weeks; Fa1=fatigue at present; Fa2=most severe fatigue in past 3 weeks; Ano1=anorexia at present; Ano2=most severe anorexia in past 3 weeks; ANX=anxiety; QOL=quality of life.
Table 6Predictors for QOL and its Subscales After Chemotherapy
*Before chemotherapy; †After 2 cycles of chemotherapy.
QOL=quality of life; Pa2=most severe pain in past 3 weeks; Fa2=most severe fatigue in past 3 weeks; Fa1=fatigue at present; Ano1=anorexia at present; Pa1=pain at present; PF=physical functioning; RP=role-physical; BP=bodily pain; GH=general health; VT=vitality; SF=social functioning; RE=role-emotional; MH=mental health.
Figure & Data
REFERENCES
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XML DownloadTransition of Symptoms and Quality of Life in Cancer Patients on Chemotherapy
Figure 1
Number of symptom experience during chemotherapy (N=76).
Figure 2
Symptom experiences during chemotherapy (multiple response).
Figure 1
Figure 2
Transition of Symptoms and Quality of Life in Cancer Patients on Chemotherapy
Demographic and Medical Characteristics of Participants (N=76)
AGC=advanced gastric cancer; OP=operation; RT=radiation therapy.
Changes in Pain, Fatigue, Anorexia, Anxiety and QOL (N=76)
*Z by Wilcoxon test.
QOL=quality of life.
Symptom Clustering and Symptom Experience by General and Medical Characteristics (N=76)
Number of Symptom Experience by General and Medical characteristics (N=76)
*Z by Mann-Whitney test; †χ2 by Kruskal-Wallis test.
AGC=advanced gastric cancer; Ca.=cancer.
Correlation between Number of Symptom, Each symptom and QOL
*Before chemotherapy; †After 2 cycles chemotherapy.
Sx.=Number of symptoms; Pa1=pain at present; Pa2=most severe pain in past 3 weeks; Fa1=fatigue at present; Fa2=most severe fatigue in past 3 weeks; Ano1=anorexia at present; Ano2=most severe anorexia in past 3 weeks; ANX=anxiety; QOL=quality of life.
Predictors for QOL and its Subscales After Chemotherapy
*Before chemotherapy; †After 2 cycles of chemotherapy.
QOL=quality of life; Pa2=most severe pain in past 3 weeks; Fa2=most severe fatigue in past 3 weeks; Fa1=fatigue at present; Ano1=anorexia at present; Pa1=pain at present; PF=physical functioning; RP=role-physical; BP=bodily pain; GH=general health; VT=vitality; SF=social functioning; RE=role-emotional; MH=mental health.
Table 1
Demographic and Medical Characteristics of Participants (N=76)
AGC=advanced gastric cancer; OP=operation; RT=radiation therapy.
Table 2
Changes in Pain, Fatigue, Anorexia, Anxiety and QOL (N=76)
*Z by Wilcoxon test. QOL=quality of life.
Table 3
Symptom Clustering and Symptom Experience by General and Medical Characteristics (N=76)
Table 4
Number of Symptom Experience by General and Medical characteristics (N=76)
*Z by Mann-Whitney test; †χ2 by Kruskal-Wallis test. AGC=advanced gastric cancer; Ca.=cancer.
Table 5
Correlation between Number of Symptom, Each symptom and QOL
*Before chemotherapy; †After 2 cycles chemotherapy. Sx.=Number of symptoms; Pa1=pain at present; Pa2=most severe pain in past 3 weeks; Fa1=fatigue at present; Fa2=most severe fatigue in past 3 weeks; Ano1=anorexia at present; Ano2=most severe anorexia in past 3 weeks; ANX=anxiety; QOL=quality of life.
Table 6
Predictors for QOL and its Subscales After Chemotherapy
*Before chemotherapy; †After 2 cycles of chemotherapy. QOL=quality of life; Pa2=most severe pain in past 3 weeks; Fa2=most severe fatigue in past 3 weeks; Fa1=fatigue at present; Ano1=anorexia at present; Pa1=pain at present; PF=physical functioning; RP=role-physical; BP=bodily pain; GH=general health; VT=vitality; SF=social functioning; RE=role-emotional; MH=mental health.
