Su Hyun Min; Su-kyoung Ko; Ji Young Lim

doi:10.4040/jkan.2008.38.3.363

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Original Article
Economic Evaluation of Gemcitabine-cisplatin Chemotherapy for Non Small-Cell Lung Cancer Patient in an Outpatient Setting: Su Hyun Min, Su-kyoung Ko, Ji Young Lim; Journal of Korean Academy of Nursing 2008;38(3):363-371.
DOI: https://doi.org/10.4040/jkan.2008.38.3.363
Published online: June 30, 2008

¹Master's Course Student, Department of Nursing, Inha University, Korea.

²Part-time Instructor, Department of Nursing, Inha University & Senior Outcomes Research Manager, Pfizer Korea, Korea.

³Professor, Department of Nursing, Inha University, Incheon, Korea.

Address reprint requests to: Lim, Ji Young. Department of Nursing, Inha University, 253 Younghyun-dong, Nam-gu, Incheon 402-751, Korea. Tel: 82-32-860-8210, Fax: 82-32-874-5880, lim20712@inha.ac.kr

• Received: November 20, 2007 • Accepted: February 1, 2008

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Abstract
NOTES
REFERENCES

Abstract

Purpose
This analysis was conducted to evaluate the cost-effectiveness of gemcitabine-cisplatin chemotherapy for non small-cell lung cancer patients in an outpatient setting compared with the traditional inpatient setting.
Methods
A cost-effective analysis was conducted from a societal perspective. The effects of treatment, which was measured as an adverse event rate, were abstracted from a published literature search and empirical data from one university hospital. The costs included both direct and indirect costs. Direct costs included hospitalizations, outpatient visits, and lab tests. Pharmaceutical costs were excluded in analysis because they were same for both options. Indirect costs included productivity loss of patients as well as care-givers. In order to determine the robustness of the results, sensitivity analysis on treatment protocol was conducted.
Results
Literature search showed no difference in adverse effect rates between inpatient treatment protocol and outpatient treatment protocol. Therefore, this analysis is a cost-minimization analysis. Cost-savings in the outpatient setting was 555,936 won for one treatment cycle. Our sensitivity analysis indicated that the outpatient chemotherapy still showed cost-savings, regardless of changes in treatment protocol.
Conclusion
The outpatient gemcitabine-cisplatin chemotherapy for non small-cell lung cancer resulted in cost savings compared to inpatient chemotherapy. More importantly, outpatient chemotherapy could improve the utilization of health service resources in terms of available beds.
Keywords: Chemotherapy; Cost effectiveness; Economics

This work was supported by Inha University Research Grant.

REFERENCES

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Figure 1

Decision analytic model for economic evaluation.

Table 1

Cost Items

Table 2

Cost of Inpatient Chemotherapy (Unit: ₩)

Table 3

Cost of Outpatient Chemotherapy (Unit: ₩)

Table 4

Sensitivity Analysis (Unit: ₩)

Figure & Data

REFERENCES

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