Journal of Korean Academy of Nursing

Original Article

Effects of Unilateral Sciatic Nerve Injury on Unaffected Hindlimb Muscles of Rats: Jin Il Kim, Myoung-Ae Choe; J Korean Acad Nurs 2009;39(3):393-400. Published online June 29, 2009; DOI: https://doi.org/10.4040/jkan.2009.39.3.393

Purpose

The purpose of this study was to examine the effects of unilateral sciatic nerve injury on unaffected hindlimb muscles of rats.

Methods

Adult male Sprague-Dawley rats were assigned to one of three groups: control (C) group (n=10) that had no procedures, sham (S) group (n=10) that underwent sham left sciatic nerve transection, and sciatic nerve transection (SNT) group (n=9) that underwent left sciatic nerve transection. At 15 days rats were anesthetized, and the soleus, plantaris and gastrocnemius muscles were dissected.

Results

Muscle weight of the unaffected plantaris muscle in the SNT group was significantly lower than in the other two groups. Type II fiber cross-sectional areas of the unaffected plantaris and gastrocnemius muscles in the SNT group were significantly smaller than in the other two groups. The decrease of muscle weights and Type I, II fiber cross-sectional areas of the unaffected three muscles in the SNT group were significantly less than that of the affected three muscles.

Conclusion

Hindlimb muscle atrophy occurs in the unaffected side after unilateral sciatic nerve injury, with changes in the plantaris and gastrocnemius muscle being more apparent than changes in the soleus muscle. These results have implications for nursing care, in the need to assess degree of muscle atrophy in unaffected muscles as well as affected muscles.

Citations

Citations to this article as recorded by

Problems in Diagnosis and Treatment of Soleus Muscle Injuries—Narrative Review and Case Report
Robert Trybulski, Kamil Gałęziok, Filip Matuszczyk, Tomasz Halski, Jarosław Muracki
Journal of Clinical Medicine.2025; 14(6): 1955. CrossRef
Assessment of ipsilateral and contralateral perfusion after contrast compression therapy of upper limb muscles in MMA athletes - a cross-over study
Robert Trybulski, Arkadiusz Stanula, Jarosław Muracki, Wacław Kuczmik, Ahmet Kurtoğlu, Jakub Taradaj
Frontiers in Physiology.2024;[Epub] CrossRef
The Impact of Sciatic Nerve Injury on Extracellular Matrix of Lower Limb Muscle and Thoracolumbar Fascia: An Observational Study
Xiaoxiao Zhao, Caterina Fede, Lucia Petrelli, Carmelo Pirri, Elena Stocco, Chenglei Fan, Andrea Porzionato, Cesare Tiengo, Raffaele De Caro, Stefano Masiero, Carla Stecco
International Journal of Molecular Sciences.2024; 25(16): 8945. CrossRef
Robot Assisted Treatment of Hand Functional Rehabilitation Based on Visual Motor Imagination
Long Li, Yanlong Zhang, Liang Huang, Jie Zhao, Jue Wang, Tian Liu
Frontiers in Aging Neuroscience.2022;[Epub] CrossRef
Therapeutic Effects of Multimodal Biophysical Stimulation on Muscle Atrophy in a Mouse Model
Seohyun Kim, Donghyun Hwang, Hana Lee, Donghyun Seo, Seungkwan Cho, Byungjo Jung, Jongbum Seo, Han Sung Kim
International Journal of Precision Engineering and Manufacturing.2018; 19(10): 1553. CrossRef
Use of Animals for Nursing Research in Korea
Hae Young Yoo
Journal of Korean Biological Nursing Science.2015; 17(4): 324. CrossRef
A Comparison between Effects of Anorexia Induced by Consecutive Low-Dose Cisplatin and High-Dose Cisplatin on Hindlimb Muscles of Rats
Jin-Il Kim, Myoung-Ae Choe
Journal of Korean Biological Nursing Science.2012; 14(1): 49. CrossRef

148 View
0 Download
7 Crossref

First
Prev
Page of 1
Next
Last

Search