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Original Articles
- A Structural Model for Chemotherapy Related Cognitive Impairment and Quality of Life in Breast Cancer Patients
- Jung Ran Lee, Pok Ja Oh
- J Korean Acad Nurs 2019;49(4):375-385. Published online January 15, 2019
- DOI: https://doi.org/10.4040/jkan.2019.49.4.375
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Abstract
PDF Abstract Purpose This study aimed to develop and test a structural model for chemotherapy-related cognitive impairment of breast cancer patients based on a literature review and Hess and Insel's chemotherapy-related cognitive change model.
Methods The Participants consisted of 250 patients who were ≥19 years of age. The assessment tools included the Menopause Rating Scale, Symptom Experience Scale, Hospital Anxiety and Depression Scale, Everyday Cognition, and Functional Assessment of Cancer Therapy-Breast Cancer. Data were analyzed using the SPSS 21.0 and AMOS 21.0 programs.
Results The modified model was a good fit for the data. The model fit indices were χ 2=423.18 (
p <.001), χ 2/df=3.38, CFI=.91, NFI=.91, TLI=.89, SRMR=.05, RMSEA=.09, and AIC=515.18. Chemotherapy-related cognitive impairment was directly influenced by menopausal symptoms (β=.38,p =.002), depression and anxiety (β=.25,p =.002), and symptom experiences (β=.19,p =.012). These predictors explained 47.7% of the variance in chemotherapy-related cognitive impairment. Depression and anxiety mediated the relations among menopausal symptoms, symptom experiences, and with chemotherapy related cognitive impairment. Depression and anxiety (β=-.51,p =.001), symptom experiences (β=-.27,p =.001), menopausal symptoms (β=-.22,p =.008), and chemotherapy-related cognitive impairment (β=-.15,p =.024) had direct effects on the quality of life and these variables explained 91.3%.Conclusion These results suggest that chemotherapy-related toxicity is highly associated with cognitive decline and quality of life in women with breast cancer. Depression and anxiety increased vulnerability to cognitive impairment after chemotherapy. Nursing intervention is needed to relieve chemotherapy-related toxicity and psychological factor as well as cognitive decline for quality of life in patients undergoing chemotherapy.
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Citations
Citations to this article as recorded by
- Analysis of Breast Cancer Nursing Education Content and Educational needs for Breast Cancer Patient Nursing Perceived by Nurses
Young-Hee Je, Kyoung-Ah Kang
Asian Oncology Nursing.2025; 25(1): 1. CrossRef - Factors Influencing Oncofertility in Gynecological Cancer Patients: Application of Mixed Methods Study
Minji Kim, Juyoung Ha
Journal of Korean Academy of Nursing.2024; 54(3): 418. CrossRef - Relationships Between Chemotherapy-Related Cognitive Impairment, Self-Care Ability, and Quality of Life in Breast Cancer Survivors: A Cross-Sectional Study
Nan Wu, Ze Luan, Zijun Zhou, He Wang, Shiyuan Du, Yulu Chen, Xinxin Wang, Jiong Li, Xin Peng
Seminars in Oncology Nursing.2024; 40(5): 151690. CrossRef - Effects of different exercise interventions on chemotherapy-related cognitive impairment in patients with breast cancer: a study protocol for systematic review and network meta-analysis
Yu Dong, Hao Huang, Aiping Wang
BMJ Open.2024; 14(4): e078934. CrossRef - Factors Associated with Self-reported Memory Problems of Adult Cancer Survivors Based on the Korea National Health and Nutrition Examination Survey 2019
Sangjin Ko
Journal of Health Informatics and Statistics.2023; 48(1): 51. CrossRef - Impact of nonpharmacological interventions on cognitive impairment in women with breast cancer: A systematic review and meta-analysis
Jin-Hee Park, Su Jin Jung, Lena J. Lee, Junghyun Rhu, Sun Hyoung Bae
Asia-Pacific Journal of Oncology Nursing.2023; 10(4): 100212. CrossRef - Impact of discriminant factors on the comfort-care of nurses caring for trans-arterial chemoembolisation patients
Myoung Soo Kim, Ju-Yeon Uhm
Supportive Care in Cancer.2022; 30(9): 7773. CrossRef - Brain morphological alterations and their correlation to tumor differentiation and duration in patients with lung cancer after platinum chemotherapy
Pin Lv, Guolin Ma, Wenqian Chen, Renyuan Liu, Xiaoyan Xin, Jiaming Lu, Shu Su, Ming Li, ShangWen Yang, Yiming Ma, Ping Rong, Ningyu Dong, Qian Chen, Xin Zhang, Xiaowei Han, Bing Zhang
Frontiers in Oncology.2022;[Epub] CrossRef - The Influence of Rehabilitation on Quality of Life in Breast Cancer Survivors: A Clinical Study
Teresa Paolucci, Aristide Saggino, Francesco Agostini, Marco Paoloni, Andrea Bernetti, Massimiliano Mangone, Valter Santilli, Raoul Saggini, Marco Tommasi
International Journal of Environmental Research and Public Health.2021; 18(16): 8585. CrossRef
- Analysis of Breast Cancer Nursing Education Content and Educational needs for Breast Cancer Patient Nursing Perceived by Nurses
- 385 View
- 6 Download
- 8 Web of Science
- 9 Crossref
- The Structural Equation Model on Resilience of Breast Cancer Patients Receiving Chemotherapy
- Jeong Ha Yang, Ok Soo Kim
- J Korean Acad Nurs 2016;46(3):327-337. Published online June 30, 2016
- DOI: https://doi.org/10.4040/jkan.2016.46.3.327
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Abstract
PDF
Purpose The purpose of this study was to construct and test a structural equation model on resilience of breast cancer patients receiving chemotherapy.
Methods Participants were 204 patients with breast cancer who received chemotherapy treatment. They participated in a structured interview, which included social support, depression, symptom experience, self-efficacy, hope, resilience, and infection prevention behaviors. Data were analyzed using SPSS/WIN 20.0 and AMOS 18.0.
Results Lower depression (γ=-.33,
p =.020) and symptom experience (γ=-.31,p =.012) and higher self-efficacy (γ=.32,p =.005) and hope (γ=.48,p =.016) were influenced by higher social support. Greater resilience was influenced by lower symptom experience (β=-.18,p =.016), higher self-efficacy (β=.49,p =.023), and higher hope (β=.46,p =.012), and these predictors explained 66.7% of variance in resilience. Greater resilience (β=.54,p =.009) made an impact on greater infection prevention behaviors. Resilience mediated the relations of symptom experience (β=-.10p =.013), self-efficacy (β=.27,p =.006) and hope (β=.25,p =.009) with infection prevention behaviors. These predictors explained 24.9% of variance in infection prevention behaviors.Conclusion The findings of the study suggest that breast cancer patientsw ith greater resilience who are receiving chemotherapy participate in increased infection prevention behaviors. Further research should be conducted to seek intervention strategies that improve breast cancer patients' resilience.
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Citations
Citations to this article as recorded by- Effects of Telephone-based Self-care Intervention for Gynecologic Cancer Patients Receiving Chemotherapy: A Quasi-Experimental Study
Boyeon Lee, Hyojung Park
Journal of Korean Academy of Fundamentals of Nursing.2023; 30(2): 216. CrossRef - Adaptación a la enfermedad, resiliencia y optimismo en mujeres con cáncer de mama
Marlen Simancas Fernández, Carla Zapata Rueda, Gonzalo Galván Patrignani, Jose Carlos Celedón Rivero, Juan Hernández Padilla
Revista Colombiana de Psiquiatría.2023; 52(4): 280. CrossRef - Adaptation to the disease, resilience and optimism in woman with breast cancer
Marlen Simancas Fernández, Carla Zapata Rueda, Gonzalo Galván Patrignani, Jose Carlos Celedón Rivero, Juan Hernández Padilla
Revista Colombiana de Psiquiatría (English ed.).2023; 52(4): 280. CrossRef - Positive personal resources and psychological distress during the COVID-19 pandemic: resilience, optimism, hope, courage, trait mindfulness, and self-efficacy in breast cancer patients and survivors
Francesca Chiesi, Deborah Vizza, Moira Valente, Rosy Bruno, Chloe Lau, Maria Rosita Campagna, Melania Lo Iacono, Francesco Bruno
Supportive Care in Cancer.2022; 30(8): 7005. CrossRef - A menopausal transition model based on transition theory
Jisoon Kim, Sukhee Ahn
Korean Journal of Women Health Nursing.2022; 28(3): 210. CrossRef - Development and Effect of the Integrated Health Promotion Program for Cancer Survivors Living at Home
Hee Sang Yoon, Eun A Hwang
Journal of Korean Academy of Community Health Nursing.2021; 32(1): 51. CrossRef - Resilience in Patients With Lung Cancer
Jie Zhang, Yizhen Yin, Anni Wang, Hui Li, Juan Li, Silan Yang, Yuchen Wu, Jingping Zhang
Cancer Nursing.2021; 44(6): 465. CrossRef - Mediator Roles of Social Support and Hope in the Relationship Between Body Image Distress and Resilience in Breast Cancer Patients Undergoing Treatment: A Modeling Analysis
Hsin-Tien Hsu, Chiung-Hui Juan, Jyu-Lin Chen, Hsiu-Fen Hsieh
Frontiers in Psychology.2021;[Epub] CrossRef - Structure Equation Modeling for Resilience in Patients with Breast Cancer
Dong Rim Hyun, So Yeun Jun, Chang Wan Jun, Sue Kyung Sohn
Korean Journal of Adult Nursing.2021; 33(2): 87. CrossRef - Factors Influencing Resilience among Korean adolescents and young adult survivors of childhood cancer
Yoon Jung Shin, Eui Geum Oh
European Journal of Oncology Nursing.2021; 53: 101977. CrossRef - Self-efficacy, Hope as Mediators Between Positive Coping and Resilience Among Patients With Gastric Cancer Before the First Chemotherapy
Xiaoting Wu, Haibo Xu, Xiaomin Zhang, Shiyu Han, Liuna Ge, Xiaohui Li, Xinqiong Zhang
Cancer Nursing.2021; 44(1): 79. CrossRef - The relationship between resilience, anxiety and depression among patients with mild symptoms of COVID‐19 in China: A cross‐sectional study
Jie Zhang, Zhen Yang, Xiao Wang, Juan Li, Lili Dong, Fusheng Wang, Yifei Li, Ruihong Wei, Jingping Zhang
Journal of Clinical Nursing.2020; 29(21-22): 4020. CrossRef - Relationship between Self-efficacy and Resilience among Patients with Colorectal Cancer with Stoma: Mediating Effects of Family Support and Medical Staff Support
Mi Na Yun, Kyoung Mi Kim
Korean Journal of Adult Nursing.2020; 32(6): 599. CrossRef - Relationship between cancer stigma, social support, coping strategies and psychosocial adjustment among breast cancer survivors
No Eul Kang, Hye Young Kim, Ji Young Kim, Sung Reul Kim
Journal of Clinical Nursing.2020; 29(21-22): 4368. CrossRef - Resilience and Its Predictors Among Chinese Liver Cancer Patients Undergoing Transarterial Chemoembolization
Caixia Li, Huijuan Lu, Wei Qin, Xiaorong Li, Jingxian Yu, Fang Fang
Cancer Nursing.2019; 42(5): E1. CrossRef - Resilience in Koreans With Cancer
Shin-Young Lee, Haeok Lee, Jacqueline Fawcett, Jeong-Hwan Park
Journal of Hospice & Palliative Nursing.2019; 21(5): 358. CrossRef - Examining spiritual support among African American and Caucasian Alzheimer's caregivers: A risk and resilience study
Scott E. Wilks, Wanda R. Spurlock, Sandra C. Brown, Bettina C. Teegen, Jennifer R. Geiger
Geriatric Nursing.2018; 39(6): 663. CrossRef - Factors Influencing Resilience in Hospitalized Patients with Stroke
Jong Kyung Lee, Ji Yeong Yun
Korean Journal of Adult Nursing.2018; 30(4): 385. CrossRef - Effects of a Group Coaching Program on Depression, Anxiety and Hope in Women with Breast Cancer Undergoing Chemotherapy
So Ryoung Seong, Moon-kyung Cho, Jeeyoon Kim, Yeo Ok Kim
Asian Oncology Nursing.2017; 17(3): 188. CrossRef
- Effects of Telephone-based Self-care Intervention for Gynecologic Cancer Patients Receiving Chemotherapy: A Quasi-Experimental Study
- 250 View
- 4 Download
- 19 Crossref
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