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5 "Randomized Controlled Trial"
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Review Papers
Effectiveness of non-pharmacological interventions to reduce internalized stigma in people with severe mental illness: a systematic review and meta-analysis
Soyoung Kim, Sun Hyoung Bae, Myung-Sun Hyun
J Korean Acad Nurs 2025;55(1):1-18.   Published online February 25, 2025
DOI: https://doi.org/10.4040/jkan.24072
AbstractAbstract PDFePub
Purpose
This study systematically reviewed and analyzed the effects of non-pharmacological interventions on internalized stigma among people with severe mental illness.
Methods
A systematic review and meta-analysis were conducted following the Cochrane Intervention Research Systematic Review Manual and Preferred Reporting Items for Systematic Review and Meta-Analysis guidelines. This study targeted people with severe mental illness as the population, interventions aimed at reducing internalized stigma, comparisons with control groups, and internalized stigma as the outcome. A literature search was performed across multiple databases, including PubMed, EMBASE, the Cochrane Library, CINAHL, PsycArticles, RISS, KMbase, and KoreaMed. The risk of bias was evaluated using the Cochrane Risk of Bias 2.0 tool. Effect sizes were computed using Hedges’s g, and subgroup analyses were conducted with Comprehensive Meta-Analysis software version 4.0.
Results
Of 2,388 papers, 15 were included in the meta-analysis. The overall effect size (Hedges’s g) of the intervention was –0.60 (95% confidence interval, –1.01 to –0.19), indicating a statistically significant reduction in internalized stigma (Z=–2.88, p=.004). Subgroup analyses revealed that the intervention type (p=.008) and session length (p=.011) were significant moderators influencing the effectiveness of the interventions.
Conclusion
Tailoring interventions by considering variables such as the intervention type and session length could enhance the effectiveness of non-pharmacological interventions for reducing internalized stigma among people with severe mental illness (PROSPERO: CRD42023418561).
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Effects of Non-Pharmacological Interventions on Major Adverse Cardiac Events in Patients Underwent Percutaneous Coronary Intervention: Systematic Review and Meta-Analysis
Jo, Sojeong , Lee, Haejung , Park, Gaeun
J Korean Acad Nurs 2024;54(3):311-328.   Published online August 31, 2024
DOI: https://doi.org/10.4040/jkan.24019
AbstractAbstract PDF
Purpose
In this study a systematic review and meta-analysis investigated the impact of non-pharmacological interventions on major adverse cardiac events (MACE) in patients with coronary artery disease who underwent percutaneous coronary intervention (PCI).
Methods
A literature search was performed using PubMed, Cochrane Library, EMBASE, and Cumulative Index to Nursing & Allied Health Literature databases up to November 2023. The risk of bias was assessed using the Cochrane Risk of Bias 2.0 tool. Effect sizes and 95% confidence intervals were calculated using R software (version 4.3.2).
Results
Eighteen randomized studies, involving 2,898 participants, were included. Of these, 16 studies with 2,697 participants provided quantitative data. Non-pharmacological interventions (education, exercise, and comprehensive) significantly reduced the risk of angina, heart failure, myocardial infarction, restenosis, cardiovascular-related readmission, and cardiovascular-related death. The subgroup meta-analysis showed that combined interventions were effective in reducing the occurrence of myocardial infarction (MI), and individual and group-based interventions had significant effects on reducing the occurrence of MACE. In interventions lasting seven months or longer, occurrence of decreased by 0.16 times, and mortality related to cardiovascular disease decreased by 0.44 times, showing that interventions lasting seven months or more were more effective in reducing MI and cardiovascular disease-related mortality.
Conclusion
Further investigations are required to assess the cost-effectiveness of these interventions in patients undergoing PCI and validate their short- and long-term effects. This systematic review underscores the potential of non-pharmacological interventions in decreasing the incidence of MACE and highlights the importance of continued research in this area (PROSPERO registration number: CRD42023462690).
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Research Paper
Effectiveness of the Eye Care Protocol in the Intensive Care Unit Patients: A Randomized Controlled Trial
Lim, Kyu Won , Ha, Shin Young , Kang, In Soon
J Korean Acad Nurs 2024;54(3):432-445.   Published online August 31, 2024
DOI: https://doi.org/10.4040/jkan.24017
AbstractAbstract PDF
Purpose
This study investigated the effects of an eye care protocol (ECP) on patients in the intensive care unit (ICU).
Methods
This study utilized a randomized controlled design. Participants were patients who met the inclusion criteria and were admitted to the ICU (36 in the experimental group and 38 in the control group). The experimental group received an ECP, while the control group received standard eye care, starting the day after admission, for a duration of 10 days. The ECP classifies the degree of eyelid obstruction into three stages based on the degree of exposure to the lower eyelid conjunctiva and cornea. The protocol included cleansing with normal saline gauze, administering eye drops, applying silicone and polyurethane films, and recommending consultation with an ophthalmologist if necessary. The effectiveness of ECP was assessed by analyzing tear volume, hyperemia, chemosis, and eye discharge. Data analysis was conducted using SPSS 27.0, employing the Mann-Whitney U-test and generalized estimating equations.
Results
On day 5, the experimental group demonstrated a significant increase in tear volume in both eyes compared with the control group. However, no statistically significant differences were observed in the incidence of hyperemia, chemosis, and eye discharge on days 5 and 10 of the intervention.
Conclusion
The application of the ECP in this study increased tear volume in ICU patients, thereby reducing discomfort caused by dry eyes. It has the potential to prevent complications such as damage to the surface of the eyeball resulting from decreased tear volume.
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Review Article
Effects of Aromatherapy on Sleep Quality: A Systematic Review and Meta-Analysis
Mi-Eun Kim, Ji Hee Jun, Muyng-Haeng Hur
J Korean Acad Nurs 2019;49(6):655-676.   Published online December 30, 2019
DOI: https://doi.org/10.4040/jkan.2019.49.6.655
AbstractAbstract PDF
Purpose

The purpose of this study was to investigate the effects of aromatherapy on sleep quality.

Methods

This is a systematic review of randomized controlled trial studies (PROSPERO registration number CRD42017064519). In this study, the PICO were adults and the elderly, aromatherapy intervention, a comparative intervention with the control and placebo oil groups, and sleep. The selected articles were in English, Korean, and Chinese.

Results

The results of the meta-analysis showed that the effect sizes of the experimental group were 1.03 (n=763, SMD=1.03, 95% CI 0.66 to 1.39) (Z=5.47, p<.001). In the aromatherapy intervention group, the effect size of sleep was statistically significant (QB=9.39, df=2, p=.009), with a difference of 0.77 for inhalation, 1.12 for oral intake and 2.05 for massage. A post-analysis showed that the effect of massage on sleep was significantly greater than the inhalation method. The regression coefficient of the intervention period, B=0.01 (Z=1.43, p=.154), also showed that the longer the intervention period, the larger the effect size; however, it was not statistically significant.

Conclusion

A total of 23 literature analyses showed that aromatherapy is effective in improving quality of sleep, and the massage method is more effective in improving quality of sleep than the inhalation method. A meta-ANOVA showed that the aromatherapy intervention affected the high heterogeneity of the effect size. Thus, future research with stricter control in methods and experimental procedures is necessary.

Citations

Citations to this article as recorded by  
  • The effects of aroma inhalation on the quality of sleep, professional quality of life, and near-misses in medication errors among emergency room nurses on night duty in Korea: a randomized controlled trial
    Jungha Son, Chul-Gyu Kim
    Journal of Korean Biological Nursing Science.2025; 27(1): 25.     CrossRef
  • Effects of a Multimodal Intervention on Sleep Quality and Duration in Intensive Care Unit Patients
    Jieun Nam, Sukhee Ahn
    Journal of Korean Critical Care Nursing.2025; 18(1): 70.     CrossRef
  • Efficacy of Aromatherapy Against Behavioral and Psychological Disturbances in People With Dementia: A Meta-Analysis of Randomized Controlled Trials
    Po-Hao Wang, Ho-Wei Lin, Truc Tran Thanh Nguyen, Chaur-Jong Hu, Li-Kai Huang, Ka-Wai Tam, Yi-Chun Kuan
    Journal of the American Medical Directors Association.2024; 25(11): 105199.     CrossRef
  • Meta-analysis of the Effect Size of Lavender Essential Oil and Lavender Blended Essential Oils on Psychological Factors in Adults
    Mi-Na Yu, Ae-Jung Kim
    Asian Journal of Beauty and Cosmetology.2024; 22(3): 477.     CrossRef
  • THE EFFECT OF LAVENDER AROMA THERAPY ON THE SLEEP QUALITY OF PREGNANT WOMEN TM III
    Hajar Nur Fathur Rohmah
    Jurnal Midpro.2024; 16(1): 59.     CrossRef
  • Effects of aromatherapy on sore throat, nasal symptoms and sleep quality in adults infected with COVID-19: A randomized controlled trial
    Hye-Young Kang, Hye Young Ahn, Mi-Jung Kang, Myung-Haeng Hur
    Integrative Medicine Research.2023; 12(4): 101001.     CrossRef
  • Pain and sleep after open-heart surgery-inhalation peppermint essence: double-blind randomized clinical trial
    Mahla Maghami, Mohammad-Sadegh Pour‑Abbasi, Safoura Yadollahi, Mahboobeh Maghami, Ismail Azizi-fini, Mohammad-Reza Afazel
    BMJ Supportive & Palliative Care.2023; 13(e3): e1318.     CrossRef
  • Effects of Aromatherapy on Cancer Patients' Sleep and Fatigue: A Systematic Review and Meta-Analysis
    Ju Hyun Ahn, Myoungsuk Kim
    Journal of Integrative and Complementary Medicine.2023; 29(4): 212.     CrossRef
  • Harnessing the power of a good night's sleep
    Karen Colombo
    Nursing Made Incredibly Easy!.2023; 21(1): 34.     CrossRef
  • Effectiveness of aromatherapy on anxiety and sleep quality among adult patients admitted into intensive care units: A systematic review
    Jie Xi Jassie Tan, Junyao Stefanie Cai, Jeanette Ignacio
    Intensive and Critical Care Nursing.2023; 76: 103396.     CrossRef
  • Fatigue relief by aromatherapy use in prenatal and postnatal women: a systematic review and meta-analysis
    Ji-Ah Song, Hyejin Yang
    Korean Journal of Women Health Nursing.2022; 28(2): 87.     CrossRef
  • Aromatherapy with single essential oils can significantly improve the sleep quality of cancer patients: a meta-analysis
    Hui Cheng, Lu Lin, Shaotong Wang, Yueyue Zhang, Tingting Liu, Yang Yuan, Qiuyun Chen, Li Tian
    BMC Complementary Medicine and Therapies.2022;[Epub]     CrossRef
  • Effects of aromatherapy on fatigue, quality of sleep and quality of life in patients with inflammatory bowel disease: A feasibility study
    Lili You, Na Guo, Tiantian Wang, Xiang Yu, Xiaofeng Kang, Yuxia Guan, Hongpeng Liu, Jing Dong, Peili Bian, Siyao Wang, Chenxiao Bai
    Complementary Therapies in Clinical Practice.2022; 49: 101648.     CrossRef
  • The Effects of Non-pharmacological Interventions on Sleep among Older Adults in Korean Long-term Care Facilities: A Systematic Review and Meta-analysis
    Sun Ok Jung, Hyeyoung Kim, Eunju Choi
    Journal of Korean Academy of Community Health Nursing.2022; 33(3): 340.     CrossRef
  • Visualizing Research Trends and Identifying Hotspots of Traditional Chinese Medicine (TCM) Nursing Technology for Insomnia: A 18-Years Bibliometric Analysis of Web of Science Core Collection
    Junxin Wang, Yufeng Chen, Xing Zhai, Yupeng Chu, Xiangdi Liu, Xueling Ma
    Frontiers in Neurology.2022;[Epub]     CrossRef
  • Effects of aromatherapy on sleep disorders
    Xin Song, Jiahua Peng, Weiyu Jiang, Minghua Ye, Lisheng Jiang
    Medicine.2021; 100(17): e25727.     CrossRef
  • Effect of aromatherapy on sleep quality of adults and elderly people: A systematic literature review and meta-analysis
    Jihoo Her, Mi-Kyoung Cho
    Complementary Therapies in Medicine.2021; 60: 102739.     CrossRef
  • Effect of Rosa damascena on improvement of adults’ sleep quality: a systematic review and meta-analysis of randomized controlled trials
    Mohammad Sadegh Ghorbani Rami, Morteza Nasiri, Mohammad Sadegh Aghili Nasab, Zohre Jafari, Mahya Torkaman, Shahoo Feizi, Behnam Farahmandnia, Masoomeh Asadi
    Sleep Medicine.2021; 87: 8.     CrossRef
  • The Mediating Effect of Sleep Quality in the Relationship between Academic Stress and Social Network Service Addiction Tendency among Adolescents
    Eun Sook Bae, Hye Seung Kang, Ha Na Lee
    Journal of Korean Academy of Community Health Nursing.2020; 31(3): 290.     CrossRef
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Original Article
Wheel of Wellness Counseling in Community Dwelling, Korean Elders: A Randomized, Controlled Trial
So-Hi Kwon
J Korean Acad Nurs 2015;45(3):459-468.   Published online June 30, 2015
DOI: https://doi.org/10.4040/jkan.2015.45.3.459
AbstractAbstract PDF
Purpose

The purpose of this study was to investigate the effects of Wheel of Wellness counseling on wellness lifestyle, depression, and health-related quality of life in community dwelling elderly people.

Methods

A parallel, randomized controlled, open label, trial was conducted. Ninety-three elderly people in a senior welfare center were randomly assigned to two groups: 1) A Wheel of Wellness counseling intervention group (n=49) and 2) a no-treatment control group (n=44). Wheel of Wellness counseling consisted of structured, individual counseling based on the Wheel of Wellness model and provided once a week for four weeks. Wellness lifestyle, depression, and health-related quality of life were assessed pre-and post-test in both groups.

Results

Data from 89 participants were analyzed. For participants in the experimental group, there was a significant improvement on all of the wellness-lifestyle subtasks except realistic beliefs. Perceived wellness and depression significantly improved after the in the experimental group (n=43) compared to the control group (n=46) from pre- to post-test in the areas of sense of control (p=.033), nutrition (p=.017), exercise (p=.039), self-care (p<.001), stress management (p=.017), work (p=.011), perceived wellness (p=.019), and depression (p=.031). One participant in the intervention group discontinued the intervention due to hospitalization and three in the control group discontinued the sessions.

Conclusion

Wheel of Wellness counseling was beneficial in enhancing wellness for the community-dwelling elderly people. Research into long-term effects of the intervention and health outcomes is recommended.

Citations

Citations to this article as recorded by  
  • The Effect of Lifestyle Interventions on Anxiety, Depression and Stress: A Systematic Review and Meta-Analysis of Randomized Clinical Trials
    Sohrab Amiri, Nailah Mahmood, Syed Fahad Javaid, Moien AB Khan
    Healthcare.2024; 12(22): 2263.     CrossRef
  • Lifestyle interventions improving health-related quality of life: A systematic review and meta-analysis of randomized control trials
    Sohrab Amiri, Nailah Mahmood, Sameeha Junaidi, Moien AB Khan
    Journal of Education and Health Promotion.2024;[Epub]     CrossRef
  • Meaning of wellness in caring science based on Rodgers's evolutionary concept analysis
    Monica Eriksson, Anette Ekström‐Bergström, Susann Arvidsson, Henrika Jormfeldt, Stina Thorstensson, Ulrica Åström, Ingela Lundgren, Åsa Roxberg
    Scandinavian Journal of Caring Sciences.2024; 38(1): 185.     CrossRef
  • Non–Exercise-Based Interventions to Support Healthy Aging in Older Adults: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
    Wei Qi Koh, Nutyathun Wora, Natasha Wing Laam Liong, Kristiana Ludlow, Nancy A Pachana, Jacki Liddle, Patricia C. Heyn
    The Gerontologist.2024;[Epub]     CrossRef
  • The Effect of Lifestyle Interventions on the International Classification of Functioning, Disability and Health Participation Domain in Older Adults: A Systematic Review and Meta-Analysis
    Sachi O’Hoski, Stephanie Chauvin, Brenda Vrkljan, Marla K Beauchamp, Patricia C Heyn
    The Gerontologist.2022; 62(6): e304.     CrossRef
  • Wellness and wellness counseling: History, status, and future
    Michael D. Brubaker, Thomas J. Sweeney
    Counselor Education and Supervision.2022; 61(1): 25.     CrossRef
  • Behaviour change techniques in personalised care planning for older people: a systematic review
    Sadia Ahmed, Anne Heaven, Rebecca Lawton, Gregg Rawlings, Claire Sloan, Andrew Clegg
    British Journal of General Practice.2021; 71(703): e121.     CrossRef
  • Lifestyle medicine for depression: A meta-analysis of randomized controlled trials
    Vincent Wing-Hei Wong, Fiona Yan-Yee Ho, Nga-Kwan Shi, Jerome Sarris, Ka-Fai Chung, Wing-Fai Yeung
    Journal of Affective Disorders.2021; 284: 203.     CrossRef
  • Intervención multidimensional preventiva de dependencia de personas mayores del centro integral para el envejecimiento feliz
    María Teresa Valenzuela, Claudia Rodríguez, Ignacio Pérez, Luis Sarmiento, Pamela San Martín
    Revista Médica Clínica Las Condes.2021; 32(4): 466.     CrossRef
  • A review on healthy ageing interventions addressing physical, mental and social health of independent community-dwelling older adults
    Betsy Seah, Yanika Kowitlawakul, Ying Jiang, Emily Ang, Srinivasan Chokkanathan, Wenru Wang
    Geriatric Nursing.2019; 40(1): 37.     CrossRef
  • Intervenções educativas para promoção da saúde do idoso: revisão integrativa
    Khelyane Mesquita de Carvalho, Cynthia Roberta Dias Torres Silva, Maria do Livramento Fortes Figueiredo, Lídya Tolstenko Nogueira, Elaine Maria Leite Rangel Andrade
    Acta Paulista de Enfermagem.2018; 31(4): 446.     CrossRef
  • Validity and reliability of a Korean version of the wellness evaluation of lifestyle (K-WEL)
    Hee Sook Kim, Yeonungsuk Song, So-Hi Kwon
    Journal of the Korean Data and Information Science Society.2016; 27(6): 1609.     CrossRef
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