Journal of Korean Academy of Nursing

Original Articles

Urinary Mutagenicity, Physical Symptoms and Stress of Nurses Handling Anticancer Drugs: Bong Im Kim; Journal of Nurses Academic Society 1996;26(4):963-975. Published online March 30, 2017; DOI: https://doi.org/10.4040/jnas.1996.26.4.963

The purpose of this study was to call attention to the mental, physical and occupational hazards of the anticancer-drug-handling nurses by examining the possible urinary mutagenicity and measuring physical symptoms and stress level of the nurses exposed to anticancer drugs. The experimental group of the urinary mutagenicity assay was 14 nurses handling anticancer drugs at the medical wards of a hospital located in J city; the control group was 12 psychiatric nurses of the same hospital. The test material was the nurses' 24hrs urine, which was concentrated by XAD-2 column chromatography. Tester strains were TA98( +/- S9 mix), TA100( +/- S9 mix), TA1535( +/- S9 mix) and TA1537( +/- S9 mix); Salmonella mammalian-microsomal test (Ames test) was employed for the urinary mutagenicity assay. The physical symptoms of which the nurses experienced were investigated through self-reports on open-questionnaires. The stress levels of the experimental group were measured by a stress measuring instrument developed by this author. Reliability of this instrument was found to be adequate (Cronbach's Alpha=0.9079). To ascertain the urinary mutagenicity of the experimental group, the mean and the standard deviation of the colonies of Tester strains appearing on the minimal plates were taken and compared differences between two groups. T-test was employed for the significance test of two groups. The physical symptoms were compared between the two groups through the analysis of the nurse' self-reports. The mean and standard deviation of the stress levels of the experimental group were also calculated and were examined through t-test. The results were summarized as follows: 1. The experimental group revealed significantly higher urinary mutagenicity both in the activation method test and the non-activation method test of the tester strains TA98, TA100 and TA1535. In the case of TA1537, two groups showed no difference in the non-activation method test, but the activation method revealed difference. 2. The physical symptoms were also much more frequently reported in the experimental group. 79. 3% of the experimental group reported more than 1 kind of physical symptoms. On the other hand, 33.2% of the control group complained of 1 kind of physical symptom. The items with high symptom frequency were 'headache', 'itching sensation', 'corneal congestion', 'skin allergy'. 3. The mean score of stress in the experimental group was 2.41(range 1-4). The experimental group showed the stress level above 2.0 in the 14 of 15 items in all. The highest stress level were recorded in the following items in the order quoted, 'I fear that anticancer drug may touch any part of body while handling it.', 'I feel concerned there is no protective countermeasure against anticancer drug handling.', 'I am afraid the anticancer drug handling may produce a fetal loss in the future'.

Citations

Citations to this article as recorded by

Knowledge and safe handling practices affecting the occupational exposure of nurses and midwives to hazardous drugs: A mixed methods systematic review
Pheona van Huizen, Philip L. Russo, Elizabeth Manias, Lisa Kuhn, Clifford J. Connell
International Journal of Nursing Studies.2024; 160: 104907. CrossRef
Effects of safe handling education on cognition, compliance and stress handling of antineoplastic drugs in clinical nurses
Eun‐Mi Jun, Se‐Won Kang
Nursing Open.2023; 10(6): 4144. CrossRef
Nurses’ Compliance with Safety Guidelines for the Use of Antineoplastic Agents, Observable Symptoms, and Stress from Occupational Exposure
Seon-Ja Park, Hyun-Ju Kim
Journal of Korean Academy of Fundamentals of Nursing.2018; 25(4): 293. CrossRef

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Relationship between Eating Disorders, Physical Symptoms, Depression and Health Locus of Control among Elementary School Girls in South Korea: Mi Hae Sung; Journal of Korean Academy of Nursing 2004;34(3):576-585. Published online March 28, 2017; DOI: https://doi.org/10.4040/jkan.2004.34.3.576

Abstract PDF

Purpose

The purpose of this study was to identify the relationship between eating disorders, physical symptoms, depression and health locus of control.

Method

The research design was a descriptive study done by using a constructive self-report questionnaire. A total of 464 elementary school girls were measured. The instrument was a constructive questionnaire that consisted 136 items. The subjects were divided into 4 groups according to the Body Mass Index (BMI). Data analysis was done by SPSS/WIN Programs using frequency, percentage, mean, SD, ANOVA, Pearson correlation coefficient, and stepwise multiple regression.

Result

The score of eating disorders differed significantly by BMI : the score was highest in the group of obese students(F=4.208, P=.015). Stepwise multiple regression analysis revealed that the most powerful predictor of eating disorders was BMI.

Conclusion

These results indicate that Korean elementary school girls need more education and counseling on diet. Also, we should take systematic efforts to reestablish the social standard of beauty to promote normal growth development.

Citations

Citations to this article as recorded by

A Study on the Correlation between Middle School Students' Eating Disorder Behavior and Scholastic Adjustment
Joo-Yeon Yoo, Yang-Ho Jin, Se-Jeong Bae
Korean Journal of Community Nutrition.2012; 17(6): 707. CrossRef
The Relation of Anger and Anger Expression to Eating Disorders in Late School-Age Children
So-Hyun Moon, Younghae Chung, Jung Hye Kim
Journal of Korean Academy of Child Health Nursing.2009; 15(2): 127. CrossRef
The Relationship between Eating Disorders and Parent-Adolescent Communication in Middle School Students in Rural Areas
Kye-Ha Kim, Kyoung-Mi Yang
Journal of Korean Academy of Nursing.2008; 38(1): 55. CrossRef

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Trajectory of Fatigue, Quality of Life and Physical Symptoms in Cancer Patients Receiving Radiotherapy: Young Hee Yang; Journal of Korean Academy of Nursing 2003;33(5):562-569. Published online March 28, 2017; DOI: https://doi.org/10.4040/jkan.2003.33.5.562

Abstract PDF

Purpose

The purpose of this longitudinal prospective study was to assess changes in fatigue and quality of life for a 6-week course of radiotherapy.

Method

A descriptive and longitudinal design was used to this study. Twenty-three subjects receiving radiotherapy from a radiotherapy clinic of a general hospital completed the questionnaires. Fatigue was measured using Lee's scale(1999) and quality of life using Yang's scale(2002) weekly for 6 weeks.

Result

Fatigue significantly increased(F=6.043, p=.000), and quality of life significantly decreased(F=3.938, p=.003) and physical symptoms also significantly increased(F=2.432, p=.039) during a 6-week radiotherapy. Multiple regression analysis revealed that fatigue at the first week and physical symptoms at the 6th week were the significant affecting variables(60.1% of the variance) on fatigue. And 63.2% of the variance in quality of life was explained by quality of life and fatigue at the first week and body weight change for 6 weeks radiotherapy.

Conclusion

Based on these results, the fatigue and quality of life at the beginning time of radiotherapy have a lasting impact throughout the course of treatment. It suggests that nurses provide patients with information about the occurrence of fatigue during radiotherapy and the practical methods of intervening physical symptoms.

Citations

Citations to this article as recorded by

A Longitudinal Path Analysis of Symptom, Fatigue and Quality of life in Patients with Colorectal Cancer during Chemotherapy
Eun Hee Kim, Soon Rim Suh
Journal of Health Informatics and Statistics.2018; 43(3): 200. CrossRef
Service improving the subjective happiness in Cancer Patient receiving Radiation Therapy
Mi Soon Song, Hyun Li Kim
Journal of Service Research and Studies.2016; 6(2): 51. CrossRef
A Model on Fatigue of Airline Flight Crew: Focus to Working Condition, Intensity of work, Compensation for Satisfaction, and Organizational Commitment
Yo-Sup Noh
Korean Comparative Government Review.2015; 19(3): 125. CrossRef
Quality of Life of Older Cancer Patients in Comparison with Older Chronic Disease Patients and Middle-Aged Cancer Patients
임연옥, Hyunsook Yoon, KIM, YOJIN
Korean Journal of Social Welfare.2013; 65(4): 367. CrossRef
Effects of a Nurse-Led Cognitive-Behavior Therapy on Fatigue and Quality of Life of Patients With Breast Cancer Undergoing Radiotherapy
Haejung Lee, Yeonjung Lim, Myung-Sook Yoo, Yongsuk Kim
Cancer Nursing.2011; 34(6): E22. CrossRef
Effects of Self-Efficacy Promotion Program on Self-Efficacy, Self-Care Behavior, and Quality of Life in Breast Cancer Patients Receiving Radiotherapy
Hea-Kyoung Ko, Geum Ja Park
Journal of Korean Oncology Nursing.2011; 11(2): 136. CrossRef
Fatigue and Quality of Life of Korean Cancer Inpatients
Hye Sun Byun, Gyung Duck Kim, Bok Yae Chung, Kyung Hye Kim
The Korean Journal of Hospice and Palliative Care.2010; 13(2): 98. CrossRef
Transition of Symptoms and Quality of Life in Cancer Patients on Chemotherapy
Min Young Kim
Journal of Korean Academy of Nursing.2009; 39(3): 433. CrossRef
Effects of a Cognitive-Behavioral Nursing Intervention on Anxiety and Depression in Women with Breast Cancer undergoing Radiotherapy
Myung-Sook Yoo, Haejung Lee, Jung-A Yoon
Journal of Korean Academy of Nursing.2009; 39(2): 157. CrossRef
Validation Study of the Korean Version of the M. D. Anderson Symptom Inventory
Young Ho Yun, Tito R. Mendoza, Im Ok Kang, Chang Hoon You, Ju Won Roh, Chang Geol Lee, Won Sup Lee, Keun Seok Lee, Soo-Mee Bang, Sang Min Park, Charles S. Cleeland, Xin Shelley Wang
Journal of Pain and Symptom Management.2006; 31(4): 345. CrossRef

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