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Effects of First Assisted Reproductive Technologies on Anxiety and Depression among InfertileWomen: A Systematic Review and Meta-Analysis
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Ju-Young Ha, Seon-Hwa Ban, Hae-Jung Lee, Misoon Lee
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J Korean Acad Nurs 2020;50(3):369-384. Published online June 30, 2020
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DOI: https://doi.org/10.4040/jkan.19187
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 Abstract
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- Purpose
The purpose of this study was to analyze anxiety and depression among infertile women at different time points during the firstIn Vitro Fertilization (IVF) or Intracytoplasmic Sperm Injection (ICSI) treatment through a systematic review and meta-analysis.
Methods
Seven out of 3,011 studies were included for meta-analysis. To estimate the effect size, a meta-analysis of the studies was performedusing the RevMan 5.3 program. We compared the measurement outcomes at three time points: before the start of treatment (T0), cancellationof treatment after pregnancy detection (T2), one to six months after treatment (T3). The effect size used was the standardizedmean difference (SMD).
Results
In comparing the different time points of the pregnant women from their cycle, significantly lower levelsof depression were found at T2 than at T0. In non-pregnant women, anxiety at T2 and depression at T2 and T3 were significantly higherthan those at T0. At T2 and T3, the non-pregnant women reported higher levels of anxiety and depression compared with the pregnantwomen.
Conclusion
Anxiety and depression in infertile women undergoing the first IVF or ICSI are associated with the time points andpregnancy status after treatment. These findings suggest that attention should be paid to helping infertile women prepare for and copewith treatment and treatment failure.
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Citations
Citations to this article as recorded by  - Effect of Stress on Each of the Stages of the IVF Procedure: A Systematic Review
Anastasia Tsambika Zanettoullis, George Mastorakos, Panagiotis Vakas, Nikolaos Vlahos, Georgios Valsamakis
International Journal of Molecular Sciences.2024; 25(2): 726. CrossRef - An Integrative Review of Psychosocial Intervention Programs for Infertile Females
Youjin Shin, Soo-Hyun Nam
STRESS.2023; 31(4): 158. CrossRef - The dynamics of mental health measures of pre- and postpartum women undergoing assisted reproductive technology
Maria E. Blokh, Varvara O. Anikina, Svetlana S. Savenysheva, Maria I. Levintsova
Journal of obstetrics and women's diseases.2023; 72(1): 17. CrossRef
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