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Effect and Path Analysis of Laughter Therapy on Serotonin, Depression and Quality of Life in Middle-aged Women
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Mi Youn Cha, Hae Sook Hong
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J Korean Acad Nurs 2015;45(2):221-230. Published online April 30, 2015
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DOI: https://doi.org/10.4040/jkan.2015.45.2.221
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Abstract
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Purpose
This study was done to examine how laughter therapy impacts serotonin levels, QOL and depression in middle-aged women and to perform a path analysis for verification of the effects.
Methods
A quasi-experimental study employing a nonequivalent control group and pre-post design was conducted. Participants were 64 middle-aged women (control=14 and experimental=50 in 3 groups according to level of depression). The intervention was conducted five times a week for a period of 2 weeks and the data analysis was conducted using repeated measures ANOVA, ANCOVA and LISREL.
Results
Results showed that pre serotonin and QOL in women with severe depression were the lowest. Serotonin in the experimental groups increased after the 10th intervention (p=.006) and the rise was the highest in the group with severe depression (p=.001). Depression in all groups decreased after the 5th intervention (p=.022) and the biggest decline was observed in group with severe depression (p=.007). QOL of the moderate and severe groups increased after the 10th intervention (p=.049), and the increase rate was highest in group with severe depression (p<.006). Path analysis revealed that laughter therapy did not directly affect depression, but its effect was indirectly meditated through serotonin variation (p<.001).
Conclusion
Results indicate that serotonin activation through laughter therapy can help middle-aged women by lessening depression and providing important grounds for depression control.
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Citations
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Aram Cho, Chiyoung Cha, Gumhee Baek Journal of Medical Internet Research.2024; 26: e54029. CrossRef - Effectiveness of yoga and laughter yoga in improving psychological resilience of mothers with babies hospitalized in neonatal intensive care unit
Zerrin Çiğdem, Emine Sarikamiş Kale, Tuba Koç Özkan Journal of Health Psychology.2024;[Epub] CrossRef - Laughter: A signal of ceased alarm toward a perceived incongruity between life and stiffness
Carlo V. Bellieni New Ideas in Psychology.2023; 68: 100977. CrossRef - Effects of laughter therapy on the stress response of married immigrant women in South Korea: A randomized controlled trial
Yejung Ko, Eun-suk Lee, Sihyun Park Health Care for Women International.2022; 43(5): 518. CrossRef - The Effect of Laughter Therapy on Physical and Mental Health: Systematic Review
Elif ÜNER, Ayşe SEZER BALCI, Hasibe KADIOĞLU Halk Sağlığı Hemşireliği Dergisi.2022; 4(3): 251. CrossRef - Effectiveness of Whole-Body Vibration Training to Improve Muscle Strength and Physical Performance in Older Adults: Prospective, Single-Blinded, Randomized Controlled Trial
Nam-Gyu Jo, Seung-Rok Kang, Myoung-Hwan Ko, Ju-Yul Yoon, Hye-Seong Kim, Kap-Soo Han, Gi-Wook Kim Healthcare.2021; 9(6): 652. CrossRef - Humor and A1C: the interaction between humor and diabetes control
David S. Greene, Nancy Dunavant King HUMOR.2021; 34(4): 483. CrossRef - Depressive Symptoms are Associated with low Serotonin Levels in Plasma but are not 5–HTTLPR Genotype Dependent in Older Adults
Pedro Enrique Trujillo-Hernández, Aide Sáenz-Galindo, Odila Saucedo-Cárdenas, María de los Ángeles Villarreal-Reyna, Mauricio Andrés Salinas-Santander, Ana Laura Carrillo-Cervantes, Reyna Torres-Obregón, Sandra Cecilia Esparza-González The Spanish Journal of Psychology.2021;[Epub] CrossRef - GELENEKSEL VE TAMAMLAYICI TIP UYGULAMALARININ GÜLEN YÜZÜ: KAHKAHA YOGASI
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David S. Greene, Nancy Dunavant King, Jean Bryan Coe Diabetes Spectrum.2020; 33(2): 175. CrossRef - Effects of a laughter programme with entrainment music on stress, depression, and health-related quality of life among gynaecological cancer patients
Yong Jin Lee, Myung Ah Kim, Hye-Ja Park Complementary Therapies in Clinical Practice.2020; 39: 101118. CrossRef - The effects of watching comedy videos on anxiety and vital signs in surgical oncology patients
Hasan Genç, Serdar Saritas EXPLORE.2020; 16(6): 401. CrossRef - Incongruent Expression of Brain-Derived Neurotrophic Factor and Cortisol in Schizophrenia: Results from a Randomized Controlled Trial of Laughter Intervention
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Karel Nešpor Cognitive Remediation Journal.2017; 6(1): 16. CrossRef - A Systematic Review of Non-pharmacological Intervention for Depression in Korean Middle-aged Women
Myung-Ock Chae, Hae Ok Jeon, Ahrin Kim Journal of the Korea Academia-Industrial cooperation Society.2016; 17(3): 638. CrossRef - Yoga and physical exercise – a review and comparison
Ramajayam Govindaraj, Sneha Karmani, Shivarama Varambally, B.N. Gangadhar International Review of Psychiatry.2016; 28(3): 242. CrossRef - Therapeutic Benefits of Laughter in Mental Health: A Theoretical Review
JongEun Yim The Tohoku Journal of Experimental Medicine.2016; 239(3): 243. CrossRef - Effects of Laughter Therapy on Immune Responses in Postpartum Women
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Transmission Aspect of Methicillin-resistant Staphylococcus aureus in the Neurosurgical Intensive Care Unit by Analysing Genotype
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Yun Kyung Kim, Hae Sook Hong
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Journal of Korean Academy of Nursing 2007;37(6):976-985. Published online March 28, 2017
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DOI: https://doi.org/10.4040/jkan.2007.37.6.976
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Abstract
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PURPOSE: The aim of this study was to identify the present situation of hospital infection and route of infection by clarifying the transmission aspect of methicillin-resistant Staphylococcus aureus(MRSA) in a Neurosurgical Intensive Care Unit by analysing genotype.
METHODS: MRSA was cultured from twenty five patients with a tracheostomy, twenty five health care workers, and environments in the Neurosurgical Intensive Care Unit of one hospital in D city. Data was collected from December 21, 2004 to November 5, 2005. MRSA isolates representing each genotype were analyzed by spaA typing and a multiplex PCR method capable of identifying the structural type of the staphylococcal cassette chromosome mec(SCCmec) carried by the bacteria.
RESULTS: As the same genotype and gene sequence were found among health care workers, patients, and environments, it was assumed that there was cross transmission among them.
CONCLUSION: This study suggests that first, as the hospital infection by MRSA between health care workers and patients in the Neurosurgical Intensive Care Unit was due to result of cross transmission and the relevance of transmission between them was verified, it is necessary to take preventive measures and conduct education. Secondly, development of nursing interventions and study of infection are needed. Thirdly, consistent investment in prevention against hospital infections and environmental renovation is needed.
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Citations
Citations to this article as recorded by 
- A Comparison between the Contamination Level of Uniforms and the Nasal Staphylococcus aureus Colonization before and after the Clinical Practice of Nursing Students
Jin Hee Park, Gisoo Shin, Jiyoung Kim Journal of Korean Biological Nursing Science.2014; 16(2): 90. CrossRef - The Effect of the Hand Hygiene Education Program on Hand Hygiene Knowledge, Hand Hygiene Perception, Nasal Staphylococcus aureus Colonization and Hand Hygiene Adherence in Nursing Students
Jin Hee Park, Hee Sun Kim Journal of Korean Biological Nursing Science.2012; 14(3): 156. CrossRef
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The Effects of the Ulmus Root-bark Dressing in Tissue Regeneration of Induced Pressure Ulcers in Rats
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Yeon Kyung Na, Hae Sook Hong
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Journal of Korean Academy of Nursing 2006;36(3):523-531. Published online June 30, 2006
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DOI: https://doi.org/10.4040/jkan.2006.36.3.523
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Abstract
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Purpose
The purpose of this study was to examine the effects of the ulmus root-bark dressing on tissue regeneration in experimentally-induced pressure ulcers in rats.
Method
A randomized pretest/post-test control group time-series study design was used. Thirty-three male Sprague-Dawley rats were used in this study. The rats were anesthetized with 100mg/kg of ketamine. Pressure ulcers were induced at 140mmHg for three hours using a personally-designed pressing apparatus. For four weeks, the ulmus root-bark dressing was applied every other day in the experimental group (n=18) and a wet gauze dressing in the control group (n=15). For data analysis, the statistical program SPSS WIN 12 was used. The wounds were examined by light microscopy and electron microscopy.
Result
There were significant statistical differences in the size of the pressure ulcers as time went by(p=0.006). It should be noted that there were no significant statistical differences in the number of capillaries. Using light microscopy the inflammatory infiltration and neovascularization in the dermis in the experimental group emerged densely in the early stages, but recovered rapidly at the latter stages. In addition, the reepithelization of the epidermis occurred earlier than in the control group. By electron microscopy, the cell organelles of the capillary endothelial cells and the basal lamina of capillaries in the experimental group showed a more rapid maturation during the latter stages, compared with the control group.
Conclusion
According to this study, it can be concluded that the ulmus root-bark dressing is effective regarding the healing of pressure ulcers.
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Citations
Citations to this article as recorded by 
- Use of Animals for Nursing Research in Korea
Hae Young Yoo Journal of Korean Biological Nursing Science.2015; 17(4): 324. CrossRef - The Effect of Ulmus Root-bark Dressing in Fibroblast Growth Factor and Vascular Endothelial Growth Factor of Induced Pressure Ulcer in Rats
Yeon Kyung Na Journal of Korean Biological Nursing Science.2013; 15(4): 257. CrossRef - Factors Affecting the Healing of Pressure Ulcers in a Korean Acute Care Hospital
Young Hee Sung, Kyung Hee Park Journal of Wound, Ostomy & Continence Nursing.2011; 38(1): 38. CrossRef
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