Dong Choon Uhm; Eun Sook Nam; Ho Yeon Lee; Eun Bong Lee; Young Im Yoon; Gong Ju Chai

doi:10.4040/jkan.2012.42.3.434

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Health-related Quality of Life in Korean Patients with Rheumatoid Arthritis: Association with Pain, Disease Activity, Disability in Activities of Daily Living and Depression: Dong Choon Uhm, Eun Sook Nam, Ho Yeon Lee, Eun Bong Lee, Young Im Yoon, Gong Ju Chai; Journal of Korean Academy of Nursing 2012;42(3):434-442.
DOI: https://doi.org/10.4040/jkan.2012.42.3.434
Published online: June 29, 2012

¹Assistant Professor, Department of Emergency Medical Technician, Daejeon University, Daejeon, South Korea.

²Professor, Department of Nursing, Health Care Research Center, Kangwon National University, Chuncheon, South Korea.

³Head Nurse, Seoul Medical Center, Seoul, South Korea.

⁴Professor, Department of Internal Medicine, Seoul National University College of Medicine, Seoul, South Korea.

⁵Nurse, Seoul National University Hospital, Seoul, South Korea.

⁶Nurse, Chuncheon National Hospital, Chuncheon, South Korea.

Address reprint requests to: Nam, Eun Sook. Department of Nursing, Gangwon National University, Hyoja 2(i)-dong, Chuncheon-si, Gangwon-do, SEOUL 200-701 Rep. of KOREA. Tel: +82-33-250-8883, Fax: +82-33-242-8840, esnam7@hanmail.net

• Received: April 7, 2011 • Accepted: May 30, 2012

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Abstract
NOTES
REFERENCES

Abstract

Purpose
The purpose of this predictive study was to identify factors affecting health related quality of life (HRQoL) in patients with rheumatoid arthritis (RA).
Methods
The participants in this study were 131 patients with RA who were recruited from the outpatient clinic of a university hospital in Seoul. Disease activity in rheumatoid arthritis was evaluated by calculating the Disease Activity Score 28. Disability in activities of daily living (ADL) was assessed with the Korean Health Assessment Questionnaire, and depression with The Center for Epidemiologic Studies Depression Scale. HRQoL was evaluated using The Short Form 36 Health Survey. Data were analyzed using descriptive statistics, correlation, and hierarchical multiple regression.
Results
Pain, disability in ADL, disease activity, and depression correlated negatively with physical and mental dimensions of HRQoL. But hierachical multiple regression analysis revealed that disability in ADL and depression were the only variables negatively influencing physical and mental QoL after adjustment for influences of sociodemographic variables.
Conclusion
Results of this study suggest that disability in ADL and depression, rather than disease activity and pain have profound effects on HRQoL in patients with RA. Further studies are needed to assess the predictive ability of disease activity and pain on HRQoL in this population.
Keywords: Rheumatoid arthritis; Health related quality of life; Pain; Disability in ADL; Depression

This work was supported by Kangwon National University, Health care research center in 2011.

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Table 1

Health related Quality of Life by Sociodemographic Variables (N=131)

QOL=Quality of life.

^*p<.05; ^**p<.01; ^†The same letters indicate nonsignificant difference between groups based on Tukey's multiple comparison test.

Table 2

Clinical, Psychological Characteristics and Quality of Life (N=131)

SD=Standard deviation; RA=Rheumatoid arthritis; ADL=Activities of daily living; KHAQ=Korean health assessment questionnaire; DAS28-ESR= Disease activity score 28-erythrocyte sedimentation rate; VAS=Visual analogue scale; QOL=Quality of life; CES-D=The center for epidemiologic studies-depression scale; SF-36=The medical outcomes study short form 36 health survey.

Table 3

Correlation Coefficients of Study Variables with Physical and Mental QOL (N=131)

RA=Rheumatoid arthritis; QOL=Quality of life; ADL=Activities of daily living.

Table 4

Factors Predicting Physical QOL (N=131)

^a=Dummy coded (married=1, single=0); ^b=Dummy coded (employed=1, unemployed=0); ^c=Dummy coded (Catholic or Protestant=1, none or Buddhist=0); VAS=Visual analogue scale; QOL=Quality of life; ADL=Activities of daily living; DAS28-ESR=Disease Activity Score 28-Erythrocyte Sedimentation Rate; KHAQ=Korean health assessment questionnaire; RA=Rheumatoid arthritis; CES-D=The Center for Epidemiologic Studies-Depression Scale.

Table 5

Factors Predicting Mental QOL (N=131)

^a=dummy coded (married=1, single=0); ^b=dummy coded (Catholic or Protestant=1, none or Buddhist=0); ^c=dummy coded (employed=1, unemployed=0); VAS=Visual analogue scale; QOL=Quality of life; ADL=Activities of daily living; DAS28-ESR=Disease Activity Score 28-Erythrocyte Sedimentation Rate; KHAQ=Korean health assessment questionnaire; RA=Rheumatoid arthritis; CES-D=The Center for Epidemiologic Studies-Depression Scale.

Figure & Data

REFERENCES

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Health-related Quality of Life in Korean Patients with Rheumatoid Arthritis: Association with Pain, Disease Activity, Disability in Activities of Daily Living and Depression

J Korean Acad Nurs. 2012;42(3):434-442. Published online June 29, 2012

DOI: https://doi.org/10.4040/jkan.2012.42.3.434

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Health-related Quality of Life in Korean Patients with Rheumatoid Arthritis: Association with Pain, Disease Activity, Disability in Activities of Daily Living and Depression

Table 1

Health related Quality of Life by Sociodemographic Variables (N=131)

QOL=Quality of life.

^*p<.05; ^**p<.01; ^†The same letters indicate nonsignificant difference between groups based on Tukey's multiple comparison test.

Table 2

Clinical, Psychological Characteristics and Quality of Life (N=131)

Table 3

Correlation Coefficients of Study Variables with Physical and Mental QOL (N=131)

RA=Rheumatoid arthritis; QOL=Quality of life; ADL=Activities of daily living.

Table 4

Factors Predicting Physical QOL (N=131)

Table 5

Factors Predicting Mental QOL (N=131)

Table 1 Health related Quality of Life by Sociodemographic Variables (N=131)

QOL=Quality of life.

^*p<.05; ^**p<.01; ^†The same letters indicate nonsignificant difference between groups based on Tukey's multiple comparison test.

Table 2 Clinical, Psychological Characteristics and Quality of Life (N=131)

Table 3 Correlation Coefficients of Study Variables with Physical and Mental QOL (N=131)